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    Your Good Partner in Biology Research

    • 中文名稱:
      ADCK4兔多克隆抗體
    • 貨號:
      CSB-PA990455
    • 規(guī)格:
      ¥2024
    • 圖片:
      • Western blot analysis of extracts from HepG2 cells, using ADCK4 antibody.
      • Immunofluorescence analysis of A549 cells, using ADCK4 antibody.
    • 其他:

    產(chǎn)品詳情

    • 產(chǎn)品名稱:
      Rabbit anti-Homo sapiens (Human) COQ8B Polyclonal antibody
    • Uniprot No.:
    • 基因名:
      COQ8B
    • 別名:
      COQ8B; ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B
    • 宿主:
      Rabbit
    • 反應種屬:
      Human,Mouse,Rat
    • 免疫原:
      Synthesized peptide derived from internal of Human ADCK4.
    • 免疫原種屬:
      Homo sapiens (Human)
    • 克隆類型:
      Polyclonal
    • 純化方式:
      The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 濃度:
      It differs from different batches. Please contact us to confirm it.
    • 產(chǎn)品提供形式:
      Liquid
    • 應用范圍:
      ELISA,WB,IF
    • 推薦稀釋比:
      Application Recommended Dilution
      WB 1:500-1:3000
      IF 1:100-1:500
    • Protocols:
    • 儲存條件:
      Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
    • 貨期:
      Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    • 用途:
      For Research Use Only. Not for use in diagnostic or therapeutic procedures.

    產(chǎn)品評價

    靶點詳情

    • 功能:
      Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration.
    • 基因功能參考文獻:
      1. Mutations in ADCK4 resulted in reduced CoQ10 levels and reduced mitochondrial respiratory enzyme activity in cells isolated from individuals with steroid-resistant nephrotic syndrome & transformed lymphoblasts. PMID: 24270420
    • 相關疾病:
      Nephrotic syndrome 9 (NPHS9)
    • 亞細胞定位:
      Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.
    • 蛋白家族:
      Protein kinase superfamily, ADCK protein kinase family
    • 組織特異性:
      Widely expressed, including renal podocytes.
    • 數(shù)據(jù)庫鏈接:

      HGNC: 19041

      OMIM: 615567

      KEGG: hsa:79934

      STRING: 9606.ENSP00000315118

      UniGene: Hs.130712



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