哎呀哎呀在线观看视频|狼狼鲁色在线视频播放|天天躁日日躁狠狠躁欧美老妇|波斯女人1977满天星|九阳真经未满十八岁能学吗|被老外做的都肿了|7tv影院

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ATG11 Antibody
  • 中文名稱：
    ATG11 Antibody
  • 貨號：
    CSB-PA622493XA01SVG
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:ATG11 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 23.5 kDa
      Observed band size: 27 kDa
      Exposure time: 10s.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ATG11 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ATG11
  • 別名：
    Autophagy-related protein 11 (Cytoplasm to vacuole targeting protein 9) ATG11 CVT9 YPR049C YP9499.07c
  • 宿主：
    Rabbit
  • 反應種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ATG11 protein (705-846aa )
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for ATG9 anterograde transport from the mitochondria to the PAS. Recruits also the ATG19-prAPE1 complex to the PAS. Required for the Cvt vesicles completion. Plays a significant role in life span extension.
  • 基因功能參考文獻：
    1. Atg11 plays important roles in low-level nonselective autophagy PMID: 28013049
    2. Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. PMID: 23858448
    3. When mitophagy is induced, Atg11 in turn attracts other mitochondrial fission proteins and promotes mitochondrial division. PMID: 23810512
    4. findings suggest that Atg11 plays an integral role in connecting cargo molecules with components of the vesicle-forming machinery PMID: 15659643
    5. Atg11 connecs cargoes, actin and pre-utophagosomal structure (PAS) elements. PMID: 16874092
    6. ATG11 is essential for selective autophagy and mitophagy PMID: 18818209

    顯示更多

    收起更多

  • 亞細胞定位：
    Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole. ATG11 localization is dependent on ATG11-ATG30 interaction.
  • 蛋白家族：
    ATG11 family
  • 數據庫鏈接：

    KEGG: sce:YPR049C

    STRING: 4932.YPR049C



×
生命科學計算平臺