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中文名稱：
CDH6兔多克隆抗體
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貨號：
CSB-PA005055ESR1HU
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規(guī)格：
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圖片：
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Western blot
All lanes: CDH6 antibody at 6μg/ml
Lane 1: 293T whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 89, 74 kDa
Observed band size: 89 kDa
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005055ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：
Rabbit anti-Homo sapiens (Human) CDH6 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：
CDH6; Cadherin-6; Kidney cadherin; K-cadherin
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宿主：
Rabbit
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反應種屬：
Human
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免疫原：
Recombinant Human Cadherin-6 protein (1-250AA)
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
Non-conjugated
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克隆類型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
Antigen Affinity Purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：
Liquid
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應用范圍：
ELISA, WB, IHC
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推薦稀釋比：
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| IHC |
1:20-1:200 |
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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基因功能參考文獻：
- Tumor suppressor genes deleted in liver cancer 1 (DLC1), F-box/WD-repeat-containing protein 7 (FBXW7), and cadherin-6 (CDH6) were identified as presumed targets in Cholangiocarcinoma (CC).Inverse correlation between promoter methylation and expression suggested miR-129-2 and members of the miR-200 family (miR-200a, miR-200b, and miR-429) as novel tumor suppressors and oncomiRs, respectively, in CC PMID: 27593557
- The chromatin modifications were determined at five PRC2 targets commonly underexpressed in multiple myeloma (CIITA, CXCL12, GATA2, CDH6 and ICSBP/IRF8). The selected genes were confirmed to be underexpressed in MM compared to normal plasma cells. PMID: 20634887
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亞細胞定位：
Cell membrane; Single-pass type I membrane protein.
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組織特異性：
Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
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數據庫鏈接：
Most popular with customers
Western blot
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005055ESR1HU at dilution of 1:100
