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  4. CLPC1 Antibody
  • 中文名稱：
    CLPC1 Antibody
  • 貨號：
    CSB-PA863761XA01DOA
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:CLPC1 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 34.5 kDa
      Observed band size: 37 kDa
      Exposure time: 10s.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CLPC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CLPC1
  • 別名：
    Chaperone protein ClpC1, chloroplastic (ATP-dependent Clp protease ATP-binding subunit ClpC homolog 1) (Casein lytic proteinase C1) (Protein DE-REGULATED CAO ACCUMULATION 1) (Protein IRON-RESCUED MUTANT 1) CLPC1 DCA1 HSP93-V IRM1 At5g50920 K3K7.7
  • 宿主：
    Rabbit
  • 反應種屬：
    Arabidopsis thaliana (Mouse-ear cress)
  • 免疫原：
    Recombinant Arabidopsis thaliana CLPC1 protein (257-504aa )
  • 免疫原種屬：
    Arabidopsis thaliana (Mouse-ear cress)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Molecular chaperone that hydrolyzes ATP and is associated with the chloroplast protein import apparatus. May function as the motor for chloroplast protein translocation, as translocation requires ATP hydrolysis in the stroma. May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast. Involved in the regulation of chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase (CAO) protein in response to the accumulation of chlorophyll b. Involved in leaf iron homeostasis.
  • 基因功能參考文獻：
    1. Data show that the loop connecting the two halves of AtClpD N-terminal domain (NTD) is longer and covers the region which in case of AtClpC1 is thought to contribute to adaptor protein interaction. PMID: 28287170
    2. indicate that CLPC1 plays a direct or indirect role in chloroplast transcriptome homeostasis PMID: 30208840
    3. Hsp93 role in protein import and proteolysis and association with chloroplast envelope. PMID: 26586836
    4. that of the two near-identical ClpC paralogs (ClpC1 and ClpC2) in Arabidopsis chloroplasts, along with the closely related ClpD, it is ClpC1 that is the most abundant throughout leaf maturation. PMID: 24599948
    5. ClpC1 is involved in leaf Fe homeostasis, presumably via chloroplast translocation of some nuclear-encoded proteins which function in Fe transport. PMID: 20382967
    6. data suggest that overall ClpC as a stromal molecular chaperone plays a vital role in chloroplast function and leaf development and is likely involved in photosystem biogenesis. [clpC1] PMID: 15563614
    7. Study indicated that a chloroplast Clp protease is involved in regulating chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase protein in response to the accumulation of chlorophyll b. PMID: 17291312
    8. cpSRP54 deletion led in young leaves to up-regulation of thylakoid proteases and stromal chaperones, including ClpC. PMID: 18633119

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  • 亞細胞定位：
    Plastid, chloroplast stroma. Plastid, chloroplast membrane.
  • 蛋白家族：
    ClpA/ClpB family, ClpC subfamily
  • 組織特異性：
    Highly expressed in rosette leaves. Expressed in roots, stems and inflorescences. Expressed in photosynthetic green tissues with high levels in young, developing leaf tissues.
  • 數據庫鏈接：

    KEGG: ath:AT5G50920

    STRING: 3702.AT5G50920.1

    UniGene: At.24774



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