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中文名稱:
DOK6兔多克隆抗體
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貨號:
CSB-PA002185
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規(guī)格:
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圖片:
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:
DOK6
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別名:
DOK6 antibody; DOK5LDocking protein 6 antibody; Downstream of tyrosine kinase 6 antibody
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宿主:
Rabbit
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反應(yīng)種屬:
Human,Mouse
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免疫原:
Synthesized peptide derived from the Internal region of Human Dok-6.
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免疫原種屬:
Homo sapiens (Human)
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標(biāo)記方式:
Non-conjugated
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抗體亞型:
IgG
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純化方式:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:
It differs from different batches. Please contact us to confirm it.
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保存緩沖液:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式:
Liquid
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應(yīng)用范圍:
WB, IHC, IF, ELISA
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推薦稀釋比:
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| IHC |
1:100-1:300 |
| IF |
1:200-1:1000 |
| ELISA |
1:10000 |
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Protocols:
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儲存條件:
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點(diǎn)詳情
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功能:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.
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基因功能參考文獻(xiàn):
- DOK-6 is involved in RET signaling with less influence when compared with DOK-1, DOK-4, and SHC. PMID: 20210798
- Dok-6 binds to the phosphorylated Ret Tyr(1062) residue resulting in phosphorylation of tyrosine residue(s) located within the unique C terminus of Dok-6 predominantly through a Src-dependent mechanism PMID: 15286081
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蛋白家族:
DOK family, Type B subfamily
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組織特異性:
Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.
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數(shù)據(jù)庫鏈接:
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