HNRNPAB Antibody, HRP conjugated

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產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) HNRNPAB Polyclonal antibody
Uniprot No.：

Q99729
基因名：

HNRNPAB
別名：

ABBP 1 antibody; ABBP-1 antibody; ABBP1 antibody; Apobec 1 binding protein 1 antibody; APOBEC1 binding protein 1 antibody; APOBEC1-binding protein 1 antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1- protein 1 antibody; FLJ40338 antibody; Heterogeneous nuclear ribonucleoprotein A/B antibody; hnRNP A/B antibody; hnRNP type A/B protein antibody; HNRNPAB antibody; HNRPAB antibody; ROAA_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Heterogeneous nuclear ribonucleoprotein A/B protein (1-68AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.
基因功能參考文獻：
1. Findings define HNRNPAB as an activator of EMT and metastasis in HCC that predicts poor clinical outcomes. PMID: 24638979
2. physical association of p63alpha and ABBP1 led to a specific shift of FGFR-2 alternative splicing toward the K-SAM isoform essential for epithelial differentiation PMID: 12692135
亞細胞定位：

Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 5034

OMIM: 602688

KEGG: hsa:3182

STRING: 9606.ENSP00000351108

UniGene: Hs.591731