Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules.
基因功能參考文獻(xiàn):
Upregulation of KIF26B enhanced proliferation and migration of ovarian cancer cells in vitro PMID: 29880787
KIF26B, a novel oncogene regulated by miR-372, promotes proliferation and metastasis through the VEGF pathway in gastric cancer PMID: 28581513
KIF26B plays an important role in colorectal carcinogenesis and functions as a novel prognostic indicator and a potential therapeutic target for CRC. PMID: 25652119
High expression of KIF26B in breast cancer associates with poor prognosis. PMID: 23585914
亞細(xì)胞定位:
Cytoplasm. Cytoplasm, cytoskeleton.
蛋白家族:
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, KIF26 subfamily