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  4. TCTN2 Antibody
  • 中文名稱：
    TCTN2兔多克隆抗體
  • 貨號：
    CSB-PA853425ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA853425ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TCTN2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TCTN2
  • 別名：
    C12orf38 antibody; FLJ12975 antibody; MKS8 antibody; OTTHUMP00000239215 antibody; OTTHUMP00000239216 antibody; Tctn2 antibody; TECT2 antibody; TECT2_HUMAN antibody; Tectonic family member 2 antibody; Tectonic-2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tectonic-2 protein (420-670AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction.
  • 基因功能參考文獻：
    1. a truncating mutation in TCTN2 linked to Meckel Gruber syndrome was shown. PMID: 21462283
    2. Network building strategy led to the proposal of candidates for new ciliopathy disease genes, leading to the identification of the first human mutations in the Nephronophthisis gene Ataxin10 (ATXN10) and Joubert syndrome gene Tectonic2 (TCTN2). PMID: 21565611
  • 相關疾病：
    Meckel syndrome 8 (MKS8); Joubert syndrome 24 (JBTS24)
  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Tectonic family
  • 數據庫鏈接：

    HGNC: 25774

    OMIM: 613846

    KEGG: hsa:79867

    STRING: 9606.ENSP00000304941

    UniGene: Hs.167165



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