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  4. fepA Antibody
  • 中文名稱：
    fepA Antibody
  • 貨號：
    CSB-PA361633XA01ENV
  • 規格：
    ￥880
  • 圖片：
    • Dot blot analysis of peptides corresponding to the immunogen was probed with fepA Antibodyat a dilution of 1:1000. Blocking/Dilution buffer: 4% nonfat dry milk/PBS. Secondary antibody：Goat polyclonal to rabbit IgG at 1/40000 dilution Exposure time: 3min.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Escherichia coli (strain K12) fepA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    fepA
  • 別名：
    Ferrienterobactin receptor (Enterobactin outer-membrane receptor) fepA fep feuB b0584 JW5086
  • 宿主：
    Rabbit
  • 反應種屬：
    Escherichia coli (strain K12)
  • 免疫原：
    Synthesized peptide derived from internal of Escherichia coli (strain K12) fepA protein (91-105aa )
  • 免疫原種屬：
    Escherichia coli (strain K12)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D.
  • 基因功能參考文獻：
    1. A stem-loop within E. coli fepA mRNA coding region activates translation initiation. PMID: 28918899
    2. TonB and FepA display confined mobility within Escherichia coli cell and inner membranes. PMID: 27935943
    3. The authors found numerous specific sites of FepA interaction with TonB on the periplasmic face of the FepA cork in addition to the TonB box. PMID: 28264993
    4. When FepA binds to ferric enterobactin in outer bacterial membrane, it was reflected by conformational motion of the external vestibular loops. PMID: 24981231
    5. analysis of the uptake of ferric enterobactin (FeEnt) by Escherichia coli FepA PMID: 20335169
    6. analysis of the mechanism of transport of ferric enterobactin through FepA PMID: 17056600
    7. TonB was required for colicin-induced exposure of the FepA TonB box, suggesting that TonB binds FepA at a different site prior to interaction with the TonB box. PMID: 17578453
    8. Modification of FepA by fluorescein maleimide was temperature-dependent, and was inhibited by colicin B binding to FepA. PMID: 19432807

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  • 亞細胞定位：
    Cell outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TonB-dependent receptor family
  • 數據庫鏈接：


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