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  4. pspA Antibody
  • 中文名稱：
    pspA Antibody
  • 貨號：
    CSB-PA360290XA01ENV
  • 規(guī)格：
    ￥880
  • 圖片：
    • Dot blot analysis of peptides corresponding to the immunogen was probed with pspA Antibodyat a dilution of 1:1000. Blocking/Dilution buffer: 4% nonfat dry milk/PBS. Secondary antibody：Goat polyclonal to rabbit IgG at 1/40000 dilution Exposure time: 10s.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Escherichia coli (strain K12) pspA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    pspA
  • 別名：
    Phage shock protein A pspA b1304 JW1297
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Escherichia coli (strain K12)
  • 免疫原：
    Synthesized peptide derived from internal of Escherichia coli (strain K12) pspA protein (17-30aa )
  • 免疫原種屬：
    Escherichia coli (strain K12)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation of the psp-specific transcriptional activator PspF. Is also required for membrane integrity, efficient translocation and maintenance of the proton motive force.
  • 基因功能參考文獻(xiàn)：
    1. Structure and function of Escherichia coli PspA and Synechocystis Vipp1 N-terminal peptides in the membrane stress sensing and mitigation have been described. PMID: 27806910
    2. Escherichia coli PspA has an enhanced sensitivity for curvature elastic (SCE) stress and a higher affinity for the membrane than Synechocystis Vipp1. PMID: 26330516
    3. The discrete spatial distribution and dynamics of PspA effector in lateral membrane regions depend on MreB and RodZ. PMID: 25118250
    4. Multiple signals are needed to induce the Psp response. PMID: 21259006
    5. These results indicate that oligomers of PspA bind to membrane phospholipids and suppress proton leakage. PMID: 17725563
    6. PspA can form hollow spherical or prolate spheroidal particles of about 30-40nm diameter with a scaffold-like arrangement of protein subunits at the surface. PMID: 18789328
    7. PspA and PspG are localized to the cell poles and traffic between both poles. PMID: 19555453

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  • 亞細(xì)胞定位：
    Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at both cell poles and along the length of the cell.
  • 蛋白家族：
    PspA/IM30 family
  • 數(shù)據(jù)庫鏈接：


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