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  4. shakB Antibody
  • 中文名稱：
    shakB Antibody
  • 貨號：
    CSB-PA335798XA01DLU
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:shakB Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 25.9 kDa
      Observed band size: 32 kDa
      Exposure time: 10s.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Drosophila melanogaster (Fruit fly) shakB Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    shakB
  • 別名：
    Innexin shaking-B (Protein passover) shakB Pas shak-B CG34358
  • 宿主：
    Rabbit
  • 反應種屬：
    Drosophila melanogaster (Fruit fly)
  • 免疫原：
    Recombinant Drosophila melanogaster (Fruit fly) shakB protein (43-110aa )
  • 免疫原種屬：
    Drosophila melanogaster (Fruit fly)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Structural component of the gap junctions at electrical synapses in distal and mid-depth levels in the lamina. Isoform Lethal forms voltage sensitive intercellular channels through homotypic interactions.
  • 基因功能參考文獻：
    1. Overexpression of ShakB(N+16) in JONs caused the formation of ectopic dye coupling PMID: 27043822
    2. Tryptophan scanning was used to probe the first transmembrane domain (M1) of the Drosophila innexin Shaking-B(Lethal). PMID: 22098739
    3. Data show that innexins, including shakB and ogre, are not functionally interchangeable in Drosophila during photoreceptor development. PMID: 12154069
    4. Seizures caused by bang-sensitive (bas2) and bang-senseless (bss1, bss2 alleles) mutations are not suppressed by shakB2 PMID: 16192342
    5. The escape response is impaired in ShakB2 mutants, but they displayed normal voluntary flight initiation. The escape mechanism is subject to developmental modulation following eclosion and the GF system does not underlie voluntary flight. PMID: 17851667

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  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
  • 蛋白家族：
    Pannexin family
  • 組織特異性：
    Isoform Neural is expressed in synapses of giant fibers (GF), in a large thoracic cell in location of postsynaptic target and optic lobe lamina and medulla. Isoform Lethal is expressed in embryonic mesodermal derivatives. During metamorphosis, both isofor
  • 數據庫鏈接：

    KEGG: dme:Dmel_CG34358

    UniGene: Dm.2607



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