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  4. tktA Antibody
  • 中文名稱：
    tktA Antibody
  • 貨號：
    CSB-PA340865ZA01ENV
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:tktA Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 85.2 kDa
      Observed band size: 81 kDa
      Exposure time: 10s.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Escherichia coli (strain K12) tktA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    tktA
  • 別名：
    Transketolase 1 (TK 1) (EC 2.2.1.1), tktA, tkt
  • 宿主：
    Rabbit
  • 反應種屬：
    Escherichia coli (strain K12)
  • 免疫原：
    Recombinant Escherichia coli tktA protein (1-663aa )
  • 免疫原種屬：
    Escherichia coli (strain K12)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Thus, catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate.
  • 基因功能參考文獻：
    1. Report the crystal structure of the S385Y/D469T/R520Q variant, and molecular docking of three substrates. This now supports our original hypothesis that directed-evolution had generated an evolutionary intermediate with divergent binding modes for the three aromatic aldehydes tested. The new active site contained two binding pockets supporting pi-pi stacking interactions, sterically separated by the D469T mutation. PMID: 27767080
    2. exponential growth-dependent expression mediated by RpoS action PMID: 15968503
    3. transketolase A interacts with MarR and interfered MarR repression of the marRAB operon. PMID: 17850260
    4. An insertion in tktA that gave synthetic growth defects in a ppGpp0 led to the identification of tktB as a transcriptional target of ppGpp. PMID: 18532980
  • 蛋白家族：
    Transketolase family
  • 數據庫鏈接：


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