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  4. Recombinant Sheep Steroidogenic acute regulatory protein, mitochondrial (STAR)

Recombinant Sheep Steroidogenic acute regulatory protein, mitochondrial (STAR)

  • 中文名稱：
    綿羊STAR重組蛋白
  • 貨號：
    CSB-YP022798SH
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    綿羊STAR重組蛋白
  • 貨號：
    CSB-EP022798SH
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    綿羊STAR重組蛋白
  • 貨號：
    CSB-EP022798SH-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    綿羊STAR重組蛋白
  • 貨號：
    CSB-BP022798SH
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    綿羊STAR重組蛋白
  • 貨號：
    CSB-MP022798SH
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    STAR; Steroidogenic acute regulatory protein; mitochondrial; StAR; START domain-containing protein 1; StARD1
  • 種屬：
    Ovis aries (Sheep)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    64-285
  • 氨基酸序列
    EDSLYSD QELAYIQQGE EAMQRALGIL KDQEGWKKES RQVNGDEVLS KVIPDVGKVF RLEVVVDQPM ERLYEELVER MEAMGEWNPS VKEIKVLQKI GKDTIITHEL AAEAAGNLVG PRDFVSVRCT KRRGSMCVLA GTATLYEEMP QQKGVIRAEH GPTCMVLRPL AGSPSRTKLT WLLSIDLKGW LPKTIINQVL SQTQVDFANH LRKRLESCPA LEARC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
  • 基因功能參考文獻：
    1. Data show that androgenization had effect on a reduction in the expression of StAR, CYP11A, CYP17, and LHR at d 90 of gestation. PMID: 21325046
    2. data show that the ovine placenta expresses steroidogenic acute regulatory protein (StAR) and adrenocorticotropic hormone receptor (ACTH-R)and there was a significant increase in the StAR mRNA and protein between 100 and 142 days of gestation PMID: 15193873
    3. data suggest that ACTH-R and StAR are key mediators of fetal adrenocortical responsiveness, and that ACTH is able to up-regulate responsiveness, and hence cortisol production, by increasing their expression PMID: 15979353
    4. These findings demonstrate that increases in circulating ACTH levels promote increased expression of ACTH-R and StAR mRNA and are coupled to heightened adrenal responsiveness. PMID: 16478774
  • 亞細胞定位：
    Mitochondrion.
  • 數(shù)據(jù)庫鏈接：

    KEGG: oas:443122

    UniGene: Oar.527



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