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  4. Recombinant Macaca mulatta Apelin receptor (APLNR)-VLPs (Active)

Recombinant Macaca mulatta Apelin receptor (APLNR)-VLPs (Active)

In Stock
  • 品名簡稱：
    Recombinant Rhesus macaque APLNR protein-VLPs (Active)
  • 貨號：
    CSB-MP001910MOW
  • 說明書：
  • 規格：
    ￥4725
  • 圖片：
    • CSB-MP001910MOW is detected by Mouse anti-6*His monoclonal antibody.
    • Activity
      Measured by its binding ability in a functional ELISA. Immobilized Macaca mulatta APLNR at 4 μg/ml can bind Anti-APLNR recombinant antibody (CSB-RA001910MA2HU). The EC50 is 20.44-25.30 ng/mL. The VLPs (CSB-MP3838) is negative control. Biological Activity Assay
    • The purity of APLNR was greater than 95% as determined by SEC-HPLC
  • 其他：

產品詳情

  • 純度：
    Greater than 95% as determined by SEC-HPLC.
  • 內毒素：
    Less than 1.0 EU/ug as determined by LAL method.
  • 生物活性：
    Measured by its binding ability in a functional ELISA. Immobilized Macaca mulatta APLNR at 4 μg/mL can bind Anti-APLNR recombinant antibody (CSB-RA001910MA2HU). The EC50 is 20.44-25.30 ng/mL. The VLPs (CSB-MP3838) is negative control.
  • 基因名：
  • Uniprot No.：
  • 別名：
    Apelin receptor; Angiotensin receptor-like 1; G-protein coupled receptor APJ
  • 種屬：
    Macaca mulatta (Rhesus macaque)
  • 蛋白長度：
    Full Length
  • 來源：
    Mammalian cell
  • 分子量：
    44.1 kDa
  • 表達區域：
    1-380aa
  • 氨基酸序列
    MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFSCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVFRTTGDLENTTKVQCYMDYSMVATVSSDWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNVFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGKGGEQMHEKSIPYSQETLVVD
  • 蛋白標簽：
    C-terminal 10xHis-tagged
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項：
    The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex.Repeated freezing and thawing is not recommended.Store the protein at -20°C/-80°C upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity. Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone. May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis. Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development. Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure.; (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：


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