ABLIM1
ABLIM1，全稱為肌動(dòng)蛋白結(jié)合LIM蛋白1，常見別名包括ABP1和LIMAB1。這種蛋白能與細(xì)胞內(nèi)的肌動(dòng)蛋白纖維結(jié)合，幫助維持細(xì)胞骨架的結(jié)構(gòu)穩(wěn)定，進(jìn)而影響細(xì)胞的形態(tài)變化、移動(dòng)能力以及細(xì)胞間的連接狀態(tài)。
在疾病關(guān)聯(lián)上，研究發(fā)現(xiàn)ABLIM1的表達(dá)異常可能與多種癌癥相關(guān)，比如乳腺癌和結(jié)直腸癌中，它的水平變化可能促進(jìn)腫瘤細(xì)胞的侵襲和轉(zhuǎn)移。此外，它也參與神經(jīng)系統(tǒng)的發(fā)育過程，其功能異常可能與某些神經(jīng)退行性疾病的發(fā)生發(fā)展存在聯(lián)系。目前針對(duì)ABLIM1的藥物研發(fā)仍處于基礎(chǔ)研究階段，科學(xué)家們主要通過解析它在細(xì)胞活動(dòng)中的具體作用，尋找潛在的干預(yù)方向，尚未有針對(duì)性藥物進(jìn)入臨床應(yīng)用階段。
熱銷產(chǎn)品
ABLIM1 Antibody (CSB-PA001107LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Hela whole cell lysate, HEK293 whole cell lysate, Mouse heart tissue
All lanes: ABLIM1 antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 88, 82, 49, 47, 53, 85 kDa
Observed band size: 88 kDa
Western Blot
Positive WB detected in: SH-SY5Y whole cell lysate, PC-3 whole cell lysate
All lanes: ABLIM1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 88, 82, 49, 47, 53, 85 kDa
Observed band size: 88, 53 kDa
ABLIM1 Antibodies
ABLIM1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001107GA01HU | ABLIM1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA914946 | ABLIM1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA242662 | ABLIM1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA001107LA01HU | ABLIM1 Antibody | Human, Mouse | ELISA, WB |
ABLIM1 Proteins
ABLIM1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001107HU CSB-EP001107HU CSB-BP001107HU CSB-MP001107HU CSB-EP001107HU-B |
Recombinant Human Actin-binding LIM protein 1 (ABLIM1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
