ADORA1
ADORA1，即腺苷A1受體，也常被稱作腺苷A1型受體。它是人體腺苷信號網絡中的關鍵成員，能與腺苷分子結合，調控多種生理活動：在神經系統(tǒng)中可調節(jié)神經細胞的興奮狀態(tài)，參與睡眠節(jié)律維持、疼痛感知等過程；在心血管系統(tǒng)里能影響血管張力和心率，助力循環(huán)系統(tǒng)穩(wěn)定運行。
ADORA1功能異?？赡芘c多種疾病關聯(lián)：癲癇發(fā)作時其活性變化可能影響神經放電；帕金森病患者的運動障礙也與它的信號異常有關；此外還可能參與心肌缺血等心血管疾病的病理過程。藥物研發(fā)領域，針對它的候選藥物正被探索——部分激動劑嘗試用于緩解慢性疼痛或預防癲癇發(fā)作，拮抗劑則可能改善某些心血管問題，不過多數(shù)藥物仍處于早期研發(fā)階段，需進一步臨床試驗驗證效果。
熱銷產品
Recombinant Human Adenosine receptor A1 (ADORA1) (CSB-CF001375HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ADORA1 Recombinant Monoclonal Antibody (CSB-RA224168A0HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: A549 whole cell lysate, 293 whole cell lysate, U87 whole cell lysate
All lanes: ADORA1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 37, 14 kDa
Observed band size: 37 kDa
IHC image of CSB-RA224168A0HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
ADORA1 Antibody (CSB-PA001375EA01HU)
驗證數(shù)據(jù)
Immunofluorescent analysis of Hela cells using CSB-PA001375EA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
ADORA1 Antibodies
ADORA1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA001375GA01HU | ADORA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA007162 | ADORA1 Antibody | Human,Rat | WB, IF, ELISA |
| CSB-PA001375EA01HU | ADORA1 Antibody | Human | ELISA, IF |
| CSB-RA224168A0HU | ADORA1 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC |
ADORA1 Proteins
ADORA1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001375DO1 CSB-EP001375DO1 CSB-BP001375DO1 CSB-MP001375DO1 CSB-EP001375DO1-B |
Recombinant Dog Adenosine receptor A1 (ADORA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001375DO | Recombinant Dog Adenosine receptor A1 (ADORA1) | in vitro E.coli expression system |
ADORA1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001375RB1 CSB-EP001375RB1 CSB-BP001375RB1 CSB-MP001375RB1 CSB-EP001375RB1-B |
Recombinant Rabbit Adenosine receptor A1 (ADORA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001375RB | Recombinant Rabbit Adenosine receptor A1 (ADORA1) | in vitro E.coli expression system |
ADORA1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001375BO1 CSB-EP001375BO1 CSB-BP001375BO1 CSB-MP001375BO1 CSB-EP001375BO1-B |
Recombinant Bovine Adenosine receptor A1 (ADORA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001375BO | Recombinant Bovine Adenosine receptor A1 (ADORA1) | in vitro E.coli expression system |
ADORA1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001375HU1 CSB-EP001375HU1 CSB-BP001375HU1 CSB-MP001375HU1 CSB-EP001375HU1-B |
Recombinant Human Adenosine receptor A1 (ADORA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001375HU | Recombinant Human Adenosine receptor A1 (ADORA1) | in vitro E.coli expression system |
| CSB-MP001375HU | Recombinant Human Adenosine receptor A1 (ADORA1)-VLPs | Mammalian cell |
ADORA1 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001375CH1 CSB-EP001375CH1 CSB-BP001375CH1 CSB-MP001375CH1 CSB-EP001375CH1-B |
Recombinant Chicken Adenosine receptor A1 (ADORA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001375CH | Recombinant Chicken Adenosine receptor A1 (ADORA1) | in vitro E.coli expression system |
ADORA1 Proteins for Cavia porcellus (Guinea pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001375GU1 CSB-EP001375GU1 CSB-BP001375GU1 CSB-MP001375GU1 CSB-EP001375GU1-B |
Recombinant Guinea pig Adenosine receptor A1 (ADORA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001375GU | Recombinant Guinea pig Adenosine receptor A1 (ADORA1) | in vitro E.coli expression system |
ADORA1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001375RA1 CSB-EP001375RA1 CSB-BP001375RA1 CSB-MP001375RA1 CSB-EP001375RA1-B |
Recombinant Rat Adenosine receptor A1 (Adora1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001375RA | Recombinant Rat Adenosine receptor A1 (Adora1) | in vitro E.coli expression system |
ADORA1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP723331MO1 CSB-EP723331MO1 CSB-BP723331MO1 CSB-MP723331MO1 CSB-EP723331MO1-B |
Recombinant Mouse Adenosine receptor A1 (Adora1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF723331MO | Recombinant Mouse Adenosine receptor A1 (Adora1) | in vitro E.coli expression system |
ADORA1 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP735863PYX1 CSB-EP735863PYX1 CSB-BP735863PYX1 CSB-MP735863PYX1 CSB-EP735863PYX1-B |
Recombinant Pongo abelii Adenosine receptor A1 (ADORA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF735863PYX | Recombinant Pongo abelii Adenosine receptor A1 (ADORA1) | in vitro E.coli expression system |
