AGTR2
AGTR2，全稱為血管緊張素II受體2型，常被簡稱為AT2受體。它是腎素-血管緊張素系統里的關鍵成員，和血管緊張素II結合后，會發揮與AT1受體相反的作用——能讓血管放松、抑制細胞過度增殖，還可能參與組織修復和神經保護。
在健康和疾病中，AGTR2和心血管系統關系密切，比如維持正常血壓、輔助心臟功能穩定，部分高血壓或心力衰竭患者的AT2受體表達會有變化；在神經系統，它可能影響神經元的存活與再生，和認知功能下降、神經退行性疾病存在一定關聯。目前針對AT2受體的藥物研發還在探索階段，一些激動劑類化合物被研究用于改善心血管問題或神經損傷，但大多處于臨床前或早期試驗，尚未有成熟藥物上市。
熱銷產品
Recombinant Human Type-2 angiotensin II receptor (AGTR2)-VLPs (CSB-MP001466HU(A4))
驗證數據
-WB.jpg)
CSB-MP001466HU(A4) is detected by Mouse anti-6*His monoclonal antibody.
-HPLC.jpg)
The purity of VLPs was greater than 95% as determined by SEC-HPLC
Recombinant Human Type-2 angiotensin II receptor (AGTR2), partial (CSB-EP001466HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
AGTR2 Recombinant Monoclonal Antibody (CSB-RA944053A0HU)
驗證數據
Western Blot
Positive WB detected in: 293T whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate, Jurkat whole cell lysate, Mouse liver tissue, Mouse heart tissue
All lanes: AGTR2 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 42 kDa
Observed band size: 42 kDa
AGTR2 Antibodies
AGTR2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA963716 | AGTR2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA944053A0HU | AGTR2 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB |
AGTR2 Proteins
AGTR2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001466MO CSB-EP001466MO CSB-BP001466MO CSB-MP001466MO CSB-EP001466MO-B |
Recombinant Mouse Type-2 angiotensin II receptor (Agtr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001466MO(A4) | Recombinant Mouse Type-2 angiotensin II receptor (Agtr2) | in vitro E.coli expression system |
AGTR2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001466RA | Recombinant Rat Type-2 angiotensin II receptor (Agtr2), partial | Yeast |
| CSB-EP001466RA | Recombinant Rat Type-2 angiotensin II receptor (Agtr2), partial | E.coli |
| CSB-BP001466RA CSB-MP001466RA CSB-EP001466RA-B |
Recombinant Rat Type-2 angiotensin II receptor (Agtr2), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AGTR2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001466HU CSB-BP001466HU CSB-MP001466HU CSB-EP001466HU-B |
Recombinant Human Type-2 angiotensin II receptor (AGTR2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP001466HU | Recombinant Human Type-2 angiotensin II receptor (AGTR2), partial | E.coli |
| CSB-MP001466HU(A4) | Recombinant Human Type-2 angiotensin II receptor (AGTR2)-VLPs | Mammalian cell |
| CSB-CF001466HU(A4) | Recombinant Human Type-2 angiotensin II receptor (AGTR2) | in vitro E.coli expression system |
AGTR2 Proteins for Ovis aries (Sheep)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP631736SH1 CSB-EP631736SH1 CSB-BP631736SH1 CSB-MP631736SH1 CSB-EP631736SH1-B |
Recombinant Sheep Type-2 angiotensin II receptor (AGTR2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF631736SH | Recombinant Sheep Type-2 angiotensin II receptor (AGTR2) | in vitro E.coli expression system |
