API5
API5，全稱為凋亡抑制蛋白5，常見別名有Anti-apoptosis protein 5。這種蛋白主要幫助細胞維持存活狀態，當細胞遇到外界壓力或內部損傷時，它能減少細胞的非正常死亡，支持細胞正常生長與分裂。它與細胞內維持增殖平衡的多個過程緊密相關，比如參與調節細胞周期的推進節奏，確保細胞在合適時機進行分裂或暫停。在疾病領域，API5的異常表達常見于肺癌、乳腺癌等癌癥中，它的過度活躍可能讓腫瘤細胞逃脫死亡機制，促進腫瘤生長和擴散。目前針對該蛋白的藥物研發處于早期探索階段，研究人員正嘗試開發能抑制其功能的小分子化合物，希望通過靶向它來阻斷腫瘤細胞的存活路徑，為癌癥治療提供新的可能。
熱銷產品
API5 Antibody (CSB-PA05559A0Rb)
驗證數據
Western Blot
Positive WB detected in: HL60 whole cell lysate, K562 whole cell lysate, Mouse spleen tissue
All lanes: API5 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 60, 50, 57, 51, 58 kDa
Observed band size: 60, 50 kDa
Immunofluorescent analysis of HepG2 cells using CSB-PA05559A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
API5 Antibodies
API5 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA000902 | API5 Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA201580 | API5 Antibody | Human | ELISA,WB |
| CSB-PA276563 | API5 Antibody | Human | ELISA,WB |
| CSB-PA540733 | API5 Antibody | Human | ELISA,WB |
| CSB-PA042409 | API5 Antibody | Human | ELISA,WB |
| CSB-PA05559A0Rb | API5 Antibody | Human, Mouse | ELISA, WB, IF |
| CSB-PA05559D0Rb | API5 Antibody, Biotin conjugated | Human | ELISA |
API5 Proteins
API5 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP001904HU CSB-EP001904HU CSB-BP001904HU CSB-MP001904HU CSB-EP001904HU-B |
Recombinant Human Apoptosis inhibitor 5 (API5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
