AQP7
AQP7，即水通道蛋白7，屬于水通道蛋白家族成員，主要分布在脂肪細(xì)胞、腎臟和骨骼肌等組織中。它的核心作用是介導(dǎo)水分和甘油的跨膜轉(zhuǎn)運(yùn)：脂肪細(xì)胞分解脂肪產(chǎn)生的甘油，需要通過它釋放到血液里，供肝臟合成葡萄糖或其他組織利用能量。
如果AQP7的功能出現(xiàn)異常，甘油可能滯留在脂肪細(xì)胞內(nèi)，打亂能量代謝的平衡，這和肥胖、2型糖尿病等代謝性疾病密切相關(guān)——比如部分2型糖尿病患者的脂肪組織中，AQP7的表達(dá)水平明顯降低，可能加重胰島素抵抗。目前針對AQP7的藥物研發(fā)還處于早期階段，一些團(tuán)隊(duì)在嘗試開發(fā)能調(diào)節(jié)其活性的小分子化合物，希望借此改善代謝紊亂，但還沒有成熟藥物應(yīng)用于臨床。
熱銷產(chǎn)品
Recombinant Human Aquaporin-7 (AQP7) (CSB-CF001967HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA276755(AQP7 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA276755(AQP7 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
AQP7 Proteins
AQP7 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001967RA1 CSB-EP001967RA1 CSB-BP001967RA1 CSB-MP001967RA1 CSB-EP001967RA1-B |
Recombinant Rat Aquaporin-7 (Aqp7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001967RA | Recombinant Rat Aquaporin-7 (Aqp7) | in vitro E.coli expression system |
AQP7 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001967HU1 CSB-EP001967HU1 CSB-BP001967HU1 CSB-MP001967HU1 CSB-EP001967HU1-B |
Recombinant Human Aquaporin-7 (AQP7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001967HU | Recombinant Human Aquaporin-7 (AQP7) | in vitro E.coli expression system |
| CSB-MP001967HU | Recombinant Human Aquaporin-7 (AQP7)-VLPs | Mammalian cell |
AQP7 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001967MO1 CSB-EP001967MO1 CSB-BP001967MO1 CSB-MP001967MO1 CSB-EP001967MO1-B |
Recombinant Mouse Aquaporin-7 (Aqp7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001967MO | Recombinant Mouse Aquaporin-7 (Aqp7) | in vitro E.coli expression system |
AQP7 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP703115MOV1 CSB-EP703115MOV1 CSB-BP703115MOV1 CSB-MP703115MOV1 CSB-EP703115MOV1-B |
Recombinant Macaca fascicularis Aquaporin-7 (AQP7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF703115MOV | Recombinant Macaca fascicularis Aquaporin-7 (AQP7) | in vitro E.coli expression system |
AQP7 Proteins for Milnesium tardigradum (Water bear) (Tardigrade)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-CF103847ZBP | Recombinant Milnesium tardigradum Aquaporin-7 (AQP7) | in vitro E.coli expression system |
