ARFGAP1
ARFGAP1，全稱為ADP核糖基化因子GTP酶激活蛋白1，常見別名包括ARF GAP 1。它在細胞內參與調控囊泡運輸過程，能促使特定小G蛋白完成活性狀態的轉換，幫助維持高爾基體的結構穩定，保證蛋白質等生物分子在細胞內的有序轉運。
ARFGAP1異常表達與多種疾病相關，尤其是腫瘤領域。例如在部分肺癌、乳腺癌細胞中，其表達水平的改變會影響細胞的增殖與遷移能力，可能成為腫瘤進展的潛在標志物。目前針對該蛋白的藥物研發仍處于早期探索階段，科研人員正嘗試開發能調節其活性的小分子化合物，期望為相關疾病的治療提供新的靶點和策略。
熱銷產品
Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) (CSB-EP843284HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ARFGAP1 Antibody (CSB-PA843284ESR2HU)
驗證數據
Western blot
All lanes: ADP-ribosylation factor GTPase-activating protein 1 antibody at 5μg/ml
Lane 1: PC-3 whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 45, 46, 32, 40 kDa
Observed band size: 45 kDa
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA843284ESR2HU at dilution of 1:100
ARFGAP1 Antibodies
ARFGAP1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA001997GA01HU | ARFGAP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA843284ESR1HU | ARFGAP1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA843284ESR2HU | ARFGAP1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA030226 | ARFGAP1 Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA122169 | ARFGAP1 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA232631 | ARFGAP1 Antibody | Human,Mouse | ELISA,WB,IHC |
ARFGAP1 Proteins
ARFGAP1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP726814RA CSB-EP726814RA CSB-BP726814RA CSB-MP726814RA CSB-EP726814RA-B |
Recombinant Rat ADP-ribosylation factor GTPase-activating protein 1 (Arfgap1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ARFGAP1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP843284HU CSB-BP843284HU CSB-MP843284HU CSB-EP843284HU-B |
Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP843284HU | Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) | E.coli |
ARFGAP1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP861667MO CSB-EP861667MO CSB-BP861667MO CSB-MP861667MO CSB-EP861667MO-B |
Recombinant Mouse ADP-ribosylation factor GTPase-activating protein 1 (Arfgap1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
