ATL2
ATL2，全稱為共濟失調性毛細血管擴張癥樣蛋白2，常用別名ATL2蛋白。它是細胞內參與DNA損傷應答與細胞周期調控的蛋白，廣泛表達于人體組織，參與DNA損傷識別、修復調控及細胞周期檢查點維持，維持基因組穩定與細胞正常生理狀態。 ATL2功能缺陷會導致DNA損傷修復異常，增加基因突變風險，與腫瘤、神經退行性疾病、免疫缺陷相關；異常表達也會打破細胞周期平衡，促進腫瘤細胞增殖。目前ATL2靶向調節劑處于臨床前研究階段，通過修復DNA損傷應答功能，為腫瘤及神經退行性疾病提供潛在治療方向。
熱銷產品
Recombinant Human ADAMTS-like protein 2 (ADAMTSL2), partial (CSB-EP801225HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ADAMTSL2 Antibody (CSB-PA105677)
驗證數據
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: K562 cells, Jurkat cells, Primary antibody: CSB-PA105677(ADAMTSL2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
Human ADAMTS-like protein 2(ADAMTSL2) ELISA kit (CSB-EL001318HU)
驗證數據
貨號：CSB-EL001318HU
規格：96T/48T
靈敏度：0.78 ng/mL
檢測范圍：3.12 ng/mL-200 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ATL2 Antibodies
ATL2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA105677 | ADAMTSL2 Antibody | Human,Mouse | ELISA,WB |
ATL2 Proteins
ATL2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP801225HU CSB-BP801225HU CSB-MP801225HU CSB-EP801225HU-B |
Recombinant Human ADAMTS-like protein 2 (ADAMTSL2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP801225HU | Recombinant Human ADAMTS-like protein 2 (ADAMTSL2), partial | E.coli |
ATL2 ELISA Kit
ATL2 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL001318HU | Human ADAMTS-like protein 2(ADAMTSL2) ELISA kit | serum, plasma, tissue homogenates | 0.78 ng/mL |
