BGLAP
BGLAP，全稱為骨鈣素，也常被稱為骨γ-羧基谷氨酸蛋白，是骨骼組織中含量豐富的非膠原蛋白之一。它既參與骨骼的礦化過程，助力維持骨骼的結構強度，又能作為一種信號分子進入血液循環，影響身體其他器官的功能——比如調節胰島素分泌，促進能量代謝，與糖脂代謝的平衡密切相關。
骨鈣素水平的異常往往和多種疾病相關：骨質疏松患者體內的骨鈣素水平通常偏低，不利于骨骼健康；部分2型糖尿病患者的骨鈣素水平也會發生改變，與代謝紊亂存在一定聯系。目前針對骨鈣素相關的研究正在推進，科學家們試圖通過調節其活性來改善骨骼問題或代謝疾病，不過相關藥物大多處于基礎研究或早期臨床試驗階段，尚未有成熟藥物上市。
熱銷產品
BGLAP Recombinant Monoclonal Antibody (CSB-RA11839MA1HU)
驗證數據
Overlay Peak curve showing U87 cells stained with CSB-RA11839MA1HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was Fluorescein (FITC) AffiniPure Goat Anti-Human IgG, Fcγ fragment specific at 1:200 dilution for 35 min at 4℃.Control antibody (green line) was human IgG1 (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
BGLAP Antibody (CSB-PA11834A0Rb)
驗證數據
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA11834A0Rb at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA11834A0Rb at dilution of 1:100
Human Osteocalcin/Bone gla protein,OT/BGP ELISA kit (CSB-E05128h)
驗證數據
貨號：CSB-E05128h
規格：96T/48T
靈敏度：7.8 pg/mL
檢測范圍：31.25 pg/ml-2000 pg/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
BGLAP Antibodies
BGLAP for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA11834C0Rb | BGLAP Antibody, FITC conjugated | Human | |
| CSB-PA11834A0Rb | BGLAP Antibody | Human | ELISA, IHC |
| CSB-PA434737 | BGLAP Antibody | Human | ELISA,IHC |
| CSB-PA277795 | BGLAP Antibody | Human | ELISA,IHC |
| CSB-PA135204 | BGLAP Antibody | Human | ELISA,IHC |
| CSB-PA944463 | BGLAP Antibody | Human | ELISA,IHC |
| CSB-RA11839MA1HU | BGLAP Recombinant Monoclonal Antibody | Human | ELISA, FC |
BGLAP Proteins
BGLAP Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP1183HU CSB-EP1183HU CSB-BP1183HU CSB-MP1183HU CSB-EP1183HU-B |
Recombinant Human Osteocalcin (BGLAP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BGLAP ELISA Kit
BGLAP ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E05128h | Human Osteocalcin/Bone gla protein,OT/BGP ELISA kit | serum, plasma, tissue homogenates | 7.8 pg/mL |
