Btc

Btc，全稱為雙調蛋白，常用別名表皮生長因子樣蛋白。它是一種分泌型表皮生長因子家族成員，廣泛表達于上皮組織、免疫細胞，參與細胞增殖、分化、遷移及炎癥反應調控，對組織修復、上皮穩態具有重要作用，同時參與腫瘤細胞的惡性進展。 Btc異常高表達與多種惡性腫瘤密切相關，在肺癌、乳腺癌、胰腺癌等腫瘤中顯著升高，能夠促進腫瘤細胞增殖、侵襲轉移及血管新生，是腫瘤不良預后的標志物。目前Btc阻斷劑及靶向抗體處于臨床前研究階段，通過抑制其促增殖活性，為實體腫瘤提供新型治療策略。

熱銷產品

Recombinant Mouse Probetacellulin (Btc), partial (Active) (CSB-MP002853MO)

驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
The ED₅₀ as determined by the dose-dMPendent stimulation of the proliferation of NIH-3T3 cells is 0.3304-0.5261 ng/mL.

Btc Antibody

Btc Protein

Btc ELISA Kit

Btc Antibodies

Btc for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA002853GA01HU	BTC Antibody	Human	ELISA,IHC
CSB-PA037451	BTC Antibody	Human	ELISA,WB
CSB-PA003854	BTC Antibody	Human	WB, ELISA
CSB-PA006305	BTC Antibody	Human	WB, ELISA

Btc Proteins

Btc Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP002853HU	Recombinant Human Probetacellulin (BTC)	Yeast
CSB-EP002853HU	Recombinant Human Probetacellulin [Cleaved into: Betacellulin protein (BTC)	E.coli
CSB-AP002871HU	Recombinant Human Probetacellulin [Cleaved into: Betacellulin protein (BTC), partial (Active)	E.Coli
CSB-CF002853HU	Recombinant Human Probetacellulin (BTC)	in vitro E.coli expression system

Btc Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP879993BO CSB-EP879993BO CSB-BP879993BO CSB-MP879993BO CSB-EP879993BO-B	Recombinant Bovine Probetacellulin (BTC), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Btc Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-MP002853MO	Recombinant Mouse Probetacellulin (Btc), partial (Active)	Mammalian cell
CSB-EP002853MO	Recombinant Mouse Probetacellulin (Btc), partial	E.coli
CSB-YP002853MO	Recombinant Mouse Probetacellulin (Btc), partial	Yeast