CACNA1D
CACNA1D，即鈣電壓門控通道CaV1.3的α1亞基，全稱為鈣電壓門控通道輔助亞基α1D，常見別名包括CACNL1A4。該蛋白是CaV1.3通道的核心功能單位，廣泛存在于心臟起搏細胞、中樞神經突觸及腎上腺等內分泌組織中。它通過調控鈣離子進入細胞，參與維持正常的心肌節律、神經遞質釋放和激素分泌過程。
CACNA1D結構或功能異常時，可能引發多種疾病：比如家族性房顫、特發性癲癇等神經心臟疾病，也與自閉癥譜系障礙、原發性醛固酮增多癥等內分泌及發育性疾病相關。目前針對CaV1.3通道的藥物研發正在推進，一些小分子調節劑已進入臨床前研究或早期臨床試驗，有望為相關難治性疾病提供新的治療方向。
熱銷產品
CACNA1D Antibody (CSB-PA745307)
驗證數據
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA745307(CACNA1D Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA745307(CACNA1D Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
CACNA1D Antibodies
CACNA1D for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA745307 | CACNA1D Antibody | Human,Rat | ELISA,IHC |
| CSB-PA123907 | CACNA1D Antibody | Human,Rat | ELISA,IHC |
| CSB-PA433325 | CACNA1D Antibody | Human,Mouse,Rat | IHC,ELISA |
| CSB-PA23409A0Rb | CACNA1D Antibody | Human | ELISA, IF |
CACNA1D Proteins
CACNA1D Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004400HU CSB-EP004400HU CSB-BP004400HU CSB-MP004400HU CSB-EP004400HU-B |
Recombinant Human Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CACNA1D Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004400RA CSB-EP004400RA CSB-BP004400RA CSB-MP004400RA CSB-EP004400RA-B |
Recombinant Rat Voltage-dependent L-type calcium channel subunit alpha-1D (Cacna1d), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CACNA1D Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004400CH CSB-EP004400CH CSB-BP004400CH CSB-MP004400CH CSB-EP004400CH-B |
Recombinant Chicken Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CACNA1D Proteins for Mesocricetus auratus (Golden hamster)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP858701MRG CSB-EP858701MRG CSB-BP858701MRG CSB-MP858701MRG CSB-EP858701MRG-B |
Recombinant Mesocricetus auratus Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CACNA1D Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP860754MO CSB-BP860754MO CSB-MP860754MO CSB-EP860754MO-B |
Recombinant Mouse Voltage-dependent L-type calcium channel subunit alpha-1D (Cacna1d), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
