CCN1
CCN1，全稱為富含半胱氨酸的分泌蛋白61（CYR61），也常被稱作結締組織生長因子家族成員1。CCN1能與細胞表面的整合素等受體相互作用，影響細胞的增殖、遷移和黏附，在血管形成、傷口愈合等生理過程中扮演角色。當它的表達出現異常時，可能參與多種疾病的發生：在腫瘤領域，它會促進腫瘤細胞生長擴散，還能助力腫瘤血管生成，常見于乳腺癌、結直腸癌等；此外，它也與肺纖維化等疾病相關，推動纖維細胞活化和基質沉積。目前針對該蛋白的藥物研發處于早期階段，一些靶向抗體藥物正在探索，希望通過抑制其功能來阻止腫瘤進展或纖維化惡化，但尚未有藥物獲批上市。
熱銷產品
Recombinant Human CCN family member 1 (CCN1) (CSB-EP006463HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CYR61 Antibody (CSB-PA10349A0Rb)
驗證數據
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA10349A0Rb at dilution of 1:100
Human cysteine-rich 61 (Cyr61/CCN1) ELISA Kit (CSB-E13884h)
驗證數據
貨號：CSB-E13884h
規格：96T/48T
靈敏度：19.5 pg/ml
檢測范圍：78 pg/mL-5000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CCN1 Antibodies
CCN1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA006463KA01HU | CYR61 Antibody | Human | ELISA,WB,IHC |
| CSB-PA10349A0Rb | CYR61 Antibody | Human | ELISA, IHC |
| CSB-PA10349D0Rb | CYR61 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA940403 | CYR61 Antibody | Human,Mouse,Rat | WB, ELISA |
CCN1 Proteins
CCN1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP006463HU CSB-BP006463HU CSB-MP006463HU CSB-EP006463HU-B |
Recombinant Human CCN family member 1 (CCN1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP002661HU | Recombinant Human CCN family member 1 (CCN1) (Active) | E.Coli |
| CSB-EP006463HU | Recombinant Human CCN family member 1 (CCN1) | E.coli |
CCN1 ELISA Kit
CCN1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13884h | Human cysteine-rich 61 (Cyr61/CCN1) ELISA Kit | serum, plasma, saliva, tissue homogenates | 19.5 pg/ml |
