CCR9
CCR9,全稱為C-C趨化因子受體9,也常被稱為CD199。它主要存在于某些T細胞表面,能與特定的信號分子結合,引導這些免疫細胞向腸道部位遷移,在腸道免疫防御和穩態維持中發揮關鍵作用。當CCR9功能失衡時,可能導致腸道免疫反應紊亂,與克羅恩病、潰瘍性結腸炎等慢性腸道炎癥疾病密切相關;部分胃腸道腫瘤細胞也會異常表達該蛋白,助力腫瘤細胞的遷移和擴散。目前針對CCR9的藥物研發聚焦于能阻斷其作用的拮抗劑,已有候選藥物進入臨床試驗階段,嘗試通過這種方式減輕腸道炎癥或抑制腫瘤進展,為相關疾病的治療提供新的方向。
熱銷產品
Recombinant Human C-C chemokine receptor type 9 (CCR9)-VLPs (Active) (CSB-MP004848HU)
驗證數據
CSB-MP004848HU is detected by Mouse anti-6*His monoclonal antibody.
The purity of VLPs was greater than 95% as determined by HPLC-SEC.
Measured by its binding ability in a functional ELISA. Immobilized Human CCR9 at 10μg/mL can bind Anti-CCR9 recombinant antibody (CSB-RA004848MA1HU),the EC50 is 31.67-36.83 ng/mL.The VLPs (CSB-MP3838) is negative control.
Recombinant Human C-C chemokine receptor type 9 (CCR9), partial (CSB-EP004848HU1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CCR9 Recombinant Monoclonal Antibody (CSB-RA004848MA1HU)
驗證數據
The Binding Activity of CCR9 with Anti-CCR9 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CCR9 at 10 μg/mL can bind Anti-CCR9 recombinant antibody (CSB-RA004848MA1HU). The EC50 is 31.67-36.83 ng/mL.The VLPs (CSB-MP3838) is negative control.
Untransfected MC38 cells (green line) and transfected Human CCR9 MC38 stable cells (red line) were stained with anti-CCR9 antibody (CSB-RA004848MA1HU) (2μg/1*106cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
CCR9 Antibodies
CCR9 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA035070 | CCR9 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA293047 | CCR9 Antibody | Human,Mouse | ELISA,IHC |
| CSB-RA004848A0HU | CCR9 Recombinant Monoclonal Antibody | Human | ELISA, IF |
| CSB-RA004848MA1HU | CCR9 Recombinant Monoclonal Antibody | Human | ELISA, FC |
CCR9 Proteins
CCR9 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004848HU1 CSB-BP004848HU1 CSB-MP004848HU1 CSB-EP004848HU1-B |
Recombinant Human C-C chemokine receptor type 9 (CCR9), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004848HU | Recombinant Human C-C chemokine receptor type 9 (CCR9) | in vitro E.coli expression system |
| CSB-EP004848HU1 | Recombinant Human C-C chemokine receptor type 9 (CCR9), partial | E.coli |
| CSB-MP004848HU | Recombinant Human C-C chemokine receptor type 9 (CCR9)-VLPs (Active) | Mammalian cell |
CCR9 Proteins for Ovis aries (Sheep)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP631240SH1 CSB-EP631240SH1 CSB-BP631240SH1 CSB-MP631240SH1 CSB-EP631240SH1-B |
Recombinant Sheep C-C chemokine receptor type 9 (CCR9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF631240SH | Recombinant Sheep C-C chemokine receptor type 9 (CCR9) | in vitro E.coli expression system |
CCR9 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP894369MO1 CSB-EP894369MO1 CSB-BP894369MO1 CSB-MP894369MO1 CSB-EP894369MO1-B |
Recombinant Mouse C-C chemokine receptor type 9 (Ccr9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF894369MO | Recombinant Mouse C-C chemokine receptor type 9 (Ccr9) | in vitro E.coli expression system |




