CES3
CES3,即羧酸酯酶3,是一種主要分布于肝臟、脂肪組織的蛋白,別名hCE-3。它能催化酯類、酰胺類化合物的水解反應,參與內源性脂質(如甘油三酯)的分解過程,幫助維持脂代謝平衡;同時也會影響多種外源性藥物的代謝效率,改變藥物在體內的作用時長與效果。在脂肪組織中,CES3表達水平與脂肪細胞分化、脂質積累密切相關,功能異常時可能導致脂代謝紊亂,增加肥胖、非酒精性脂肪肝等代謝性疾病的發生風險。此外,它對部分降脂藥、抗病毒藥的代謝有顯著影響,可能引發藥效降低或不良反應。目前,研究人員正探索CES3調節劑的開發,希望通過調控其活性改善代謝性疾病癥狀,或優化藥物組合方案以減少代謝相關的用藥問題,為相關疾病治療提供新方向。
熱銷產品
Recombinant Human Carboxylesterase 3 (CES3) (CSB-EP005260HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CES3 Antibody (CSB-PA005260LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA005260LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005260LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA005260LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
CES3 Antibodies
CES3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA005260GA01HU | CES3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA005260LA01HU | CES3 Antibody | Human | ELISA, IHC, IF |
CES3 Proteins
CES3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-BP005260HU CSB-MP005260HU CSB-EP005260HU-B |
Recombinant Human Carboxylesterase 3 (CES3) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP005260HU | Recombinant Human Carboxylesterase 3 (CES3) | Yeast |
| CSB-EP005260HU | Recombinant Human Carboxylesterase 3 (CES3) | E.coli |




