CHRNA7
CHRNA7，全稱為α7煙堿型乙酰膽堿受體，常被簡稱為α7受體。它是神經細胞表面的一種關鍵蛋白質，能與乙酰膽堿結合，參與大腦的學習、記憶及注意力調控過程。這種受體的功能變化與多種疾病密切相關：精神分裂癥患者常存在CHRNA7受體的功能異常，表現為認知障礙；阿爾茨海默病患者大腦中該受體的數量或活性下降，可能加劇記憶衰退；此外，它還與某些神經發育疾病的癥狀關聯。在藥物研發方面，目前有多個候選藥物針對α7受體展開研究，試圖通過調節其活性改善相關疾病的癥狀，部分已進入臨床試驗階段，但尚未有成熟的靶向藥物獲批上市。
熱銷產品
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CHRNA7 Antibody (CSB-PA969473)
驗證數據
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA969473(CHRFAM7A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA969473(CHRFAM7A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA969473(CHRFAM7A Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
CHRNA7 Antibodies
CHRNA7 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA969473 | CHRNA7 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA188517 | CHRNA7 Antibody | Human, Mouse, Rat | ELISA, WB |
CHRNA7 Proteins
CHRNA7 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005393CH CSB-EP005393CH CSB-BP005393CH CSB-MP005393CH CSB-EP005393CH-B |
Recombinant Chicken Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHRNA7 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005393HU CSB-EP005393HU CSB-BP005393HU CSB-MP005393HU |
Recombinant Human Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), partial | Yeast E.coli Baculovirus Mammalian cell |
| CSB-EP005393HUa0 | Recombinant Human Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), partial | E.coli |
| CSB-EP005393HU-B | Recombinant Human Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), partial, Biotinylated | E.coli |
| CSB-EP005393HUg2 | Recombinant Human Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), partial | E.coli |
CHRNA7 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005393MO CSB-BP005393MO CSB-MP005393MO CSB-EP005393MO-B |
Recombinant Mouse Neuronal acetylcholine receptor subunit alpha-7 (Chrna7), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHRNA7 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005393BO CSB-EP005393BO CSB-BP005393BO CSB-MP005393BO CSB-EP005393BO-B |
Recombinant Bovine Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHRNA7 Proteins for Macaca mulatta (Rhesus macaque)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005393MOW CSB-EP005393MOW CSB-BP005393MOW CSB-MP005393MOW CSB-EP005393MOW-B |
Recombinant Macaca mulatta Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
