CHRNG
CHRNG，全稱為煙堿型乙酰膽堿受體γ亞基，常被簡稱為乙酰膽堿受體γ亞單位。它是神經(jīng)與肌肉連接區(qū)域關鍵受體的核心組成部分，能幫助神經(jīng)信號順利傳遞到肌肉細胞，支撐肌肉完成正常收縮動作。當CHRNG出現(xiàn)異常時，神經(jīng)到肌肉的信號傳遞會受阻，可能引發(fā)肌肉無力相關疾病——比如部分先天性肌無力綜合征患者，就是因CHRNG基因突變，出生后出現(xiàn)吸吮困難、肢體軟弱甚至呼吸乏力等癥狀。目前臨床常用藥物可增強神經(jīng)信號傳遞效率，暫時改善肌肉力量；科研人員也在探索針對具體突變的靶向治療，希望從根源解決問題，提升患者的生活質(zhì)量。
熱銷產(chǎn)品
Recombinant Human Acetylcholine receptor subunit gamma (CHRNG), partial (CSB-EP005401HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CHRNG Antibody (CSB-PA005401ESR2HU)
驗證數(shù)據(jù)
Western blot
All lanes: CHRNG antibody at 5.5μg/ml
Lane 1: 293T whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 58, 53 kDa
Observed band size: 58 kDa
CHRNG Antibodies
CHRNG for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA005401ESR2HU | CHRNG Antibody | Human | ELISA, WB |
CHRNG Proteins
CHRNG Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005401HU | Recombinant Human Acetylcholine receptor subunit gamma (CHRNG), partial | Yeast |
| CSB-BP005401HU CSB-MP005401HU CSB-EP005401HU-B |
Recombinant Human Acetylcholine receptor subunit gamma (CHRNG), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP005401HU | Recombinant Human Acetylcholine receptor subunit gamma (CHRNG), partial | E.coli |
