CLEC9A
CLEC9A，全稱為C型凝集素結構域家族9成員A，常用別名為DNGR-1。這種蛋白主要分布在一類特殊的樹突狀細胞表面，能識別壞死細胞釋放的核酸等物質，進而觸發后續的免疫應答，幫助機體清除受損或異常的細胞。
在疾病方面，CLEC9A功能異常可能與自身免疫性疾病相關，比如某些炎癥性疾病中，它介導的免疫反應過度激活會加重組織損傷；而在腫瘤領域，它可以啟動針對腫瘤細胞的免疫攻擊，因此成為免疫治療的潛在靶點。目前針對CLEC9A的藥物研發處于早期階段，研究人員嘗試開發能激活它的制劑來增強抗腫瘤免疫，或通過調節其活性緩解自身免疫病，相關臨床試驗仍在探索中。
熱銷產品
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Anti-CLEC9A recombinant antibody (CSB-RA740922MA1HU) at 2 μg/ml can bind Human CLEC9A protein. The EC50 is 2.915-3.520 ng/mL.
CLEC9A Recombinant Monoclonal Antibody (CSB-RA740922MA1HU)
驗證數據
The Binding Activity of Human CLEC9A with Anti-CLEC9A recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Anti-CLEC9A recombinant antibody at 2 μg/mL can bind Human CLEC9A protein (CSB-MP740922HU-B). The EC50 is 2.915-3.520 ng/mL.
Human C-type lectin domain family 9 member A(CLEC9A) ELISA kit (CSB-EL005542HU)
驗證數據
貨號：CSB-EL005542HU
規格：96T/48T
靈敏度：0.078 ng/mL
檢測范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CLEC9A Antibodies
CLEC9A for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA740922HA01HU | CLEC9A Antibody | Human, Mouse | ELISA, WB, IF |
| CSB-PA740922HB01HU | CLEC9A Antibody, HRP conjugated | Human | ELISA |
| CSB-PA740922HC01HU | CLEC9A Antibody, FITC conjugated | Human | |
| CSB-PA740922HD01HU | CLEC9A Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA740922MA1HU | CLEC9A Recombinant Monoclonal Antibody | Human | ELISA |
CLEC9A Proteins
CLEC9A Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005542RA1 CSB-EP005542RA1 CSB-BP005542RA1 CSB-MP005542RA1 CSB-EP005542RA1-B |
Recombinant Rat C-type lectin domain family 9 member A (Clec9a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005542RA | Recombinant Rat C-type lectin domain family 9 member A (Clec9a) | in vitro E.coli expression system |
CLEC9A Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP740922HU CSB-BP740922HU CSB-MP740922HU CSB-EP740922HU-B |
Recombinant Human C-type lectin domain family 9 member A (CLEC9A), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP740922HU-B | Recombinant Human C-type lectin domain family 9 member A (CLEC9A), partial, Biotinylated (Active) | Mammalian cell |
| CSB-YP740922HU | Recombinant Human C-type lectin domain family 9 member A (CLEC9A), partial | Yeast |
CLEC9A Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP806896MO CSB-EP806896MO CSB-BP806896MO CSB-MP806896MO CSB-EP806896MO-B |
Recombinant Mouse C-type lectin domain family 9 member A (Clec9a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CLEC9A ELISA Kit
CLEC9A ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL005542HU | Human C-type lectin domain family 9 member A(CLEC9A) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.078 ng/mL |
