COL4A1
COL4A1，全稱為 IV 型膠原蛋白 α1 鏈，常用別名基底膜膠原 4A1。它是機體基底膜核心結構蛋白，廣泛分布于血管、腎臟、視網膜、腦基底膜，維持基底膜完整致密結構，保障血管屏障、腎臟濾過、血腦屏障穩定正常功能。
COL4A1 基因突變及表達異常會引發遺傳性腦血管病、腦小血管病、腎病、視網膜病變等多系統遺傳性疾病，同時異常重塑也參與腫瘤基底膜破壞、腫瘤侵襲轉移進程。目前針對 COL4A1 結構修復與功能調控療法處于臨床前研究，為遺傳性血管腎病及惡性腫瘤提供全新潛在干預方案。
熱銷產品
Recombinant Human Collagen alpha-1 (IV) chain (COL4A1), partial (CSB-EP005741HU1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
COL4A1 Antibody (CSB-PA11464A0Rb)
驗證數據
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA11464A0Rb at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA11464A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
COL4A1 Antibodies
COL4A1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA11464A0Rb | COL4A1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA11469B0Rb | COL4A1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA11469A0Rb | COL4A1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA975386 | COL4A1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA001748 | COL4A1 Antibody | Human, Mouse | WB, IHC, ELISA |
| CSB-PA972442 | COL4A1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA294012 | COL4A1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-MA212614 | COL4A1 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-MA457742 | COL4A1 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-MA211140 | COL4A1 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-MA562279 | COL4A1 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-MA176252 | COL4A1 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-MA145731 | COL4A1 Monoclonal Antibody | Human,Mouse,Rat | ELISA,IHC |
COL4A1 Proteins
COL4A1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005741HU CSB-BP005741HU CSB-MP005741HU CSB-EP005741HU-B |
Recombinant Human Collagen alpha-1 (IV) chain (COL4A1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP005741HU1 | Recombinant Human Collagen alpha-1 (IV) chain (COL4A1), partial | E.coli |
| CSB-EP005741HU | Recombinant Human Collagen alpha-1 (IV) chain (COL4A1), partial | E.coli |
COL4A1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005741MO CSB-BP005741MO CSB-MP005741MO CSB-EP005741MO-B |
Recombinant Mouse Collagen alpha-1 (IV) chain (Col4a1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
COL4A1 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP742450BO CSB-EP742450BO CSB-BP742450BO CSB-MP742450BO CSB-EP742450BO-B |
Recombinant Bovine Collagen alpha-1 (IV) chain (COL4A1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
COL4A1 ELISA Kit
COL4A1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL005741HU | Human Collagen alpha-1(IV) chain (COL4A1) ELISA kit | serum, plasma, tissue homogenates | 7.81 pg/mL |
