CRISPLD1
CRISPLD1，全稱為富含半胱氨酸 LCCL 結(jié)構(gòu)域分泌蛋白 1，無(wú)通用常用別名。它是一種分泌型胞外基質(zhì)蛋白，主要分布于細(xì)胞外微環(huán)境，參與細(xì)胞外基質(zhì)結(jié)構(gòu)維持、組織損傷修復(fù)、細(xì)胞黏附遷移調(diào)控以及胚胎正常發(fā)育分化，對(duì)機(jī)體組織完整結(jié)構(gòu)穩(wěn)定、生理功能正常運(yùn)行起到重要支撐作用。
CRISPLD1 表達(dá)異常紊亂與肺癌、肝癌、胰腺癌等多種實(shí)體惡性腫瘤密切相關(guān)，異常分泌表達(dá)會(huì)重塑腫瘤微環(huán)境，顯著促進(jìn)腫瘤細(xì)胞侵襲、遷移與遠(yuǎn)處轉(zhuǎn)移，是腫瘤預(yù)后不良的重要預(yù)測(cè)指標(biāo)。目前該靶點(diǎn)基礎(chǔ)研究較為深入，但靶向干預(yù)藥物開(kāi)發(fā)仍處于早期臨床前探索階段，具備良好的抗腫瘤靶向治療開(kāi)發(fā)潛力與應(yīng)用價(jià)值。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
-SDS.jpg)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CRISPLD1 Antibody (CSB-PA884457LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA884457LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA884457LA01HU at dilution of 1:100
CRISPLD1 Antibodies
CRISPLD1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA884457LA01HU | CRISPLD1 Antibody | Human | ELISA, IHC |
CRISPLD1 Proteins
CRISPLD1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP884457HU CSB-EP884457HU CSB-BP884457HU CSB-MP884457HU CSB-EP884457HU-B |
Recombinant Human Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF884457HU | Recombinant Human Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) | in vitro E.coli expression system |
| CSB-CF884457HU(M1) | Recombinant Human Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) (R431H) | in vitro E.coli expression system |
| CSB-CF884457HU(M) | Recombinant Human Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) (G371D) | in vitro E.coli expression system |
