CSF2RB
CSF2RB，全稱為粒細胞-巨噬細胞集落刺激因子受體β亞基，常見別名包括GM-CSFRβ和CD131。它是一種跨膜蛋白，需與α亞基結合形成完整受體，才能響應體內特定信號分子，調控粒細胞、巨噬細胞等免疫細胞的生長、分化與功能發揮。
CSF2RB功能變化與多種疾病相關：若其介導的信號過強，可能推動自身免疫性疾病或慢性炎癥的發展；若功能缺陷，則可能導致免疫細胞生成障礙，引發免疫低下相關病癥。在藥物研發方面，針對該蛋白的靶向藥物正被探索用于控制過度炎癥或治療血液系統疾病，部分候選藥物已進入臨床試驗階段，有望為相關疾病患者提供新的治療選擇。
熱銷產品
Recombinant Human Cytokine receptor common subunit beta (CSF2RB), partial (Active) (CSB-MP006047HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized CSF2RB at 2 μg/ml can bind anti-CSF2RB antibody（CSB-RA006047A0HU）, the EC50 is 0.1594-0.3046 ng/mL.
CSF2RB Recombinant Monoclonal Antibody (CSB-RA006047A0HU)
驗證數據
The Binding Activity of CSF2RB with anti-CSF2RB antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CSF2RB(CSB-MP006047HU) at 2 μg/mL can bind Anti-CSF2RB recombinant antibody, the EC50 is 0.1594-0.3046 ng/mL.
CSF2RB Antibodies
CSF2RB for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA003029 | CSF2RB Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA007339 | Phospho-CSF2RB (Y593) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA200894 | CSF2RB Antibody | Human | ELISA,IHC |
| CSB-PA598159 | CSF2RB Antibody | Human | ELISA,IHC |
| CSB-PA006047LA01HU | CSF2RB Antibody | Human | ELISA, IHC, IF |
| CSB-RA006047A0HU | CSF2RB Recombinant Monoclonal Antibody | Human | ELISA |
| CSB-RA006047MA1HU | CSF2RB Recombinant Monoclonal Antibody | Human | ELISA, IF |
CSF2RB Proteins
CSF2RB Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP006047MO CSB-EP006047MO CSB-BP006047MO CSB-MP006047MO CSB-EP006047MO-B |
Recombinant Mouse Cytokine receptor common subunit beta (Csf2rb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSF2RB Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP006047HU CSB-EP006047HU CSB-BP006047HU CSB-EP006047HU-B |
Recombinant Human Cytokine receptor common subunit beta (CSF2RB), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP006047HU | Recombinant Human Cytokine receptor common subunit beta (CSF2RB), partial (Active) | Mammalian cell |
