CST3
CST3，全稱為半胱氨酸蛋白酶抑制劑 C，常用別名胱抑素 C。它是一種全身廣泛分泌表達(dá)的小分子蛋白酶抑制蛋白，能夠抑制組織內(nèi)蛋白酶過度降解，調(diào)控細(xì)胞外基質(zhì)重塑、組織代謝平衡，同時(shí)血清中表達(dá)水平穩(wěn)定，是臨床上公認(rèn)靈敏可靠的腎功能評估標(biāo)志物。
CST3 表達(dá)異常升高與腎功能損傷、慢性腎病、動(dòng)脈粥樣硬化、腦退行性病變以及顱內(nèi)腫瘤密切相關(guān)，表達(dá)紊亂會(huì)加劇組織異常重塑、慢性炎癥損傷，加速疾病進(jìn)展惡化。目前 CST3 主要用于臨床疾病監(jiān)測診斷，針對該蛋白功能調(diào)控的特異性靶向藥物仍處于臨床前基礎(chǔ)研究階段，有望為慢性腎病、腦血管及腦部腫瘤相關(guān)疾病提供新型干預(yù)思路。
熱銷產(chǎn)品
CST3 Recombinant Monoclonal Antibody (CSB-RA810605A0HU)
驗(yàn)證數(shù)據(jù)
Western blotting analysis using cystatin C antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with cystatin C antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
CST3 Antibody (CSB-PA06197A0Rb)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: CST3 antibody at 2µg/ml
Lane 1: High values of serum at 1: 10
Lane 2: High values of serum at 1: 100
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 16 kDa
Observed band size: 16 kDa
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA06197A0Rb at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA06197A0Rb at dilution of 1:100
Human Cystatin C,Cys-C ELISA Kit (CSB-E08384h)
驗(yàn)證數(shù)據(jù)
貨號：CSB-E08384h
規(guī)格：96T/48T
靈敏度：5.824 ng/mL
檢測范圍：7.8 ng/mL-500 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CST3 Antibodies
CST3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA06196A0Rb | CST3 Antibody | Human | ELISA, WB, IHC |
| CSB-PA06196B0Rb | CST3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA06196C0Rb | CST3 Antibody, FITC conjugated | Human | |
| CSB-PA006091GA01HU | CST3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA06197B0Rb | CST3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA002010 | CST3 Antibody | Human,Mouse,Rat,Monkey | WB, ELISA |
| CSB-PA592744 | CST3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA205008 | CST3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA06197A0Rb | CST3 Antibody | Human | ELISA, WB, IHC |
| CSB-RA810605A0HU | CST3 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB |
CST3 Proteins
CST3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006091HU CSB-EP006091HU CSB-BP006091HU CSB-MP006091HU CSB-EP006091HU-B |
Recombinant Human Cystatin-C (CST3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CST3 ELISA Kit
CST3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08384h | Human Cystatin C,Cys-C ELISA Kit | serum, plasma, urine, saliva, tissue homogenates | 5.824 ng/mL |
