DNASE1L3
DNASE1L3，全稱為脫氧核糖核酸酶1樣蛋白3，也常被稱為DNase gamma。它的核心功能是清除體內多余的細胞外DNA——這些DNA多來自凋亡細胞或細胞碎片。一旦該蛋白功能異常，細胞外DNA就會堆積，可能被免疫系統誤判為外來入侵物，從而觸發異常的免疫攻擊。
目前已知，DNASE1L3缺陷或基因突變與系統性紅斑狼瘡等自身免疫疾病高度相關，許多患者體內存在該蛋白活性降低或針對它的自身抗體。在藥物研發方面，科學家們正探索通過補充該蛋白或調節其活性來緩解自身免疫病癥狀，不過相關研究還處于早期階段，尚未有成熟藥物投入臨床使用。
熱銷產品
Recombinant Human Deoxyribonuclease gamma (DNASE1L3) (CSB-BP621686HUb1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
DNASE1L3 Antibody (CSB-PA621686EA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA621686EA01HU at dilution of 1:100
Human Deoxyribonuclease gamma(DNASE1L3) ELISA kit (CSB-EL007052HU)
驗證數據
貨號：CSB-EL007052HU
規格：96T/48T
靈敏度：5.86 pg/mL
檢測范圍：23.44 pg/mL-1500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
DNASE1L3 Antibodies
DNASE1L3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA007052GA01HU | DNASE1L3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA115883 | DNASE1L3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA621686EA01HU | DNASE1L3 Antibody | Human | ELISA, IHC |
| CSB-PA621686EB01HU | DNASE1L3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA621686EC01HU | DNASE1L3 Antibody, FITC conjugated | Human | |
| CSB-PA621686ED01HU | DNASE1L3 Antibody, Biotin conjugated | Human | ELISA |
DNASE1L3 Proteins
DNASE1L3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007052MO CSB-BP007052MO CSB-MP007052MO CSB-EP007052MO-B |
Recombinant Mouse Deoxyribonuclease gamma (Dnase1l3) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP007052MO | Recombinant Mouse Deoxyribonuclease gamma (Dnase1l3) | E.coli |
| CSB-EP007052MOb0 | Recombinant Mouse Deoxyribonuclease gamma (Dnase1l3) | E.coli |
DNASE1L3 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007052RA CSB-EP007052RA CSB-BP007052RA CSB-MP007052RA CSB-EP007052RA-B |
Recombinant Rat Deoxyribonuclease gamma (Dnase1l3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DNASE1L3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP621686HU CSB-MP621686HU CSB-EP621686HU-B |
Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP621686HU | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | E.coli |
| CSB-BP621686HU | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | Baculovirus |
| CSB-EP621686HUe1 | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | E.coli |
| CSB-BP621686HUb1 | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | Baculovirus |
| CSB-EP621686HUb1 | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | E.coli |
| CSB-EP621686HUc7 | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | E.coli |
| CSB-EP621686HUd7 | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | E.coli |
| CSB-EP621686HUg5 | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | E.coli |
| CSB-EP621686HUa0 | Recombinant Human Deoxyribonuclease gamma (DNASE1L3) | E.coli |
DNASE1L3 ELISA Kit
DNASE1L3 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL007052HU | Human Deoxyribonuclease gamma(DNASE1L3) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 5.86 pg/mL |
