ELOVL1
ELOVL1，全稱為超長鏈脂肪酸延長酶1，也常被稱為ELOVL家族成員1。它主要參與超長鏈脂肪酸的合成，這些脂肪酸是細胞膜、神經鞘脂等結構的關鍵組成部分，對維持神經細胞正常功能、細胞間信息傳遞有著重要作用。
當ELOVL1功能異常時，可能導致脂質代謝失衡，進而引發疾病，比如遺傳性痙攣性截癱——患者會出現下肢肌肉痙攣、行走障礙等癥狀，這與ELOVL1突變影響神經鞘脂合成密切相關。目前針對相關疾病的藥物研發仍處于基礎探索階段，科研人員正研究通過調控其活性改善脂質代謝，但尚未有針對性藥物進入臨床，未來有望為這類疾病提供新的治療方向。
熱銷產品
Recombinant Human Very long chain fatty acid elongase 1 (ELOVL1) (CSB-CF887138HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ELOVL1 Antibody (CSB-PA887138LA01HU)
驗證數據
Immunofluorescent analysis of MCF-7 cells using CSB-PA887138LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA887138LA01HU at dilution of 1:100
ELOVL1 Antibodies
ELOVL1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA262320 | ELOVL1 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA002321 | ELOVL1 Antibody | Human,Mouse | WB, ELISA |
| CSB-PA934646 | ELOVL1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA939360 | ELOVL1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA887138LA01HU | ELOVL1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA887138LD01HU | ELOVL1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA887138LC01HU | ELOVL1 Antibody, FITC conjugated | Human | |
| CSB-PA887138LB01HU | ELOVL1 Antibody, HRP conjugated | Human | ELISA |
ELOVL1 Proteins
ELOVL1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP887138HU1 CSB-EP887138HU1 CSB-BP887138HU1 CSB-MP887138HU1 CSB-EP887138HU1-B |
Recombinant Human Elongation of very long chain fatty acids protein 1 (ELOVL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF887138HU | Recombinant Human Very long chain fatty acid elongase 1 (ELOVL1) | in vitro E.coli expression system |
