ERVW-1
ERVW-1，全稱為合胞體滋養(yǎng)層糖蛋白1，簡稱為Syncytin-1。它是胎盤發(fā)育里的關(guān)鍵分子，能推動滋養(yǎng)層細(xì)胞相互融合，形成合胞體滋養(yǎng)層結(jié)構(gòu)——這層細(xì)胞既是母體與胎兒間營養(yǎng)、氣體交換的重要通道，還能分泌維持妊娠的必要激素。ERVW-1表達(dá)或功能出現(xiàn)異常，可能干擾胎盤的正常運(yùn)作，和子癇前期、胎兒生長受限等妊娠相關(guān)問題有關(guān)；部分研究還發(fā)現(xiàn)，它在絨毛膜癌等生殖系統(tǒng)腫瘤中也存在異常表達(dá)。目前針對它的研究多聚焦于妊娠并發(fā)癥的干預(yù)和腫瘤治療靶點開發(fā)，比如嘗試通過調(diào)控其活性改善胎盤功能，或設(shè)計靶向藥物抑制腫瘤細(xì)胞中的異常表達(dá)，但這些探索大多仍處于實驗室階段，尚未進(jìn)入臨床應(yīng)用。
熱銷產(chǎn)品
Recombinant Human Syncytin-1 (ERVW-1), partial (CSB-EP891578HUb0)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ERVW-1 Antibody (CSB-PA891578LA01HU)
驗證數(shù)據(jù)
Immunofluorescent analysis of HepG2 cells using CSB-PA891578LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human testicle tissue using CSB-PA891578LA01HU at dilution of 1:300
ERVW-1 Antibodies
ERVW-1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA997932 | ERVW-1 Antibody | Human | ELISA,IHC |
| CSB-PA215261 | ERVW-1 Antibody | Human | ELISA,IHC |
| CSB-PA891578LA01HU | ERVW-1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA891578LB01HU | ERVW-1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA891578LC01HU | ERVW-1 Antibody, FITC conjugated | Human | |
| CSB-PA891578LD01HU | ERVW-1 Antibody, Biotin conjugated | Human | ELISA |
ERVW-1 Proteins
ERVW-1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YPCSB-YP891578HU CSB-EPCSB-YP891578HU-B |
Recombinant Human Syncytin-1 (ERVW-1), partial | Yeast In Vivo Biotinylation in E.coli |
| CSB-EP891578HU | Recombinant Human Syncytin-1 (ERVW-1), partial | E.coli |
| CSB-BP891578HU CSB-MP891578HU CSB-EP891578HU-B |
Recombinant Human Syncytin-1 (ERVW-1), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP891578HUb0 | Recombinant Human Syncytin-1 (ERVW-1), partial | E.coli |
| CSB-EP891578HUc7 | Recombinant Human Syncytin-1 (ERVW-1), partial | E.coli |
