FLG
絲聚蛋白（Filaggrin，F(xiàn)LG蛋白）是皮膚表皮角質(zhì)層的核心結(jié)構(gòu)蛋白，無特殊常見別名。它能讓角質(zhì)細(xì)胞緊密聚集形成堅(jiān)固的皮膚屏障，還可分解為天然保濕因子，維持皮膚水潤狀態(tài)。當(dāng)FLG相關(guān)功能異常時(shí)，皮膚屏障易受損，不僅會導(dǎo)致干燥、脫屑，還常與特應(yīng)性皮炎（濕疹）發(fā)病密切相關(guān)，部分人群還可能因此增加過敏性鼻炎、哮喘等過敏問題的風(fēng)險(xiǎn)。
目前針對FLG缺陷的干預(yù)以修復(fù)皮膚屏障為主，比如外用保濕劑、角質(zhì)修復(fù)產(chǎn)品已廣泛應(yīng)用；同時(shí)科研人員也在探索更針對性的治療，像促進(jìn)絲聚蛋白合成的小分子化合物、補(bǔ)充其前體物質(zhì)的制劑，部分項(xiàng)目已進(jìn)入早期臨床試驗(yàn)階段，有望為相關(guān)患者提供更精準(zhǔn)的解決方案。
熱銷產(chǎn)品
Recombinant Human Filaggrin (FLG), partial (CSB-EP008712HUa6)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
FLG Antibody (CSB-PA008712HA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA008712HA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA008712HA01HU at dilution of 1:100
Human Filaggrin(FLG) ELISA kit (CSB-EL008712HU)
驗(yàn)證數(shù)據(jù)
貨號：CSB-EL008712HU
規(guī)格：96T/48T
靈敏度：5.8 pg/mL
檢測范圍：23.5 pg/mL-1500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
FLG Antibodies
FLG for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA008712HA01HU | FLG Antibody | Human | ELISA, IHC |
| CSB-PA008712HB01HU | FLG Antibody, HRP conjugated | Human | ELISA |
| CSB-PA008712HD01HU | FLG Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA235658 | FLG Antibody | Human | ELISA,IHC |
| CSB-PA247101 | FLG Antibody | Human | ELISA,IHC |
FLG Proteins
FLG Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP008712MO CSB-EP008712MO CSB-BP008712MO CSB-MP008712MO CSB-EP008712MO-B |
Recombinant Mouse Filaggrin (Flg) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FLG Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP008712HU | Recombinant Human Filaggrin (FLG), partial | Yeast |
| CSB-EP008712HU | Recombinant Human Filaggrin (FLG), partial | E.coli |
| CSB-BP008712HU | Recombinant Human Filaggrin (FLG), partial | Baculovirus |
| CSB-MP008712HU CSB-EP008712HU-B |
Recombinant Human Filaggrin (FLG), partial | Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP008712HUa6 | Recombinant Human Filaggrin (FLG), partial | E.coli |
| CSB-EP008712HU2 | Recombinant Human Filaggrin (FLG), partial | E.coli |
FLG ELISA Kit
FLG ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL008712HU | Human Filaggrin(FLG) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 5.8 pg/mL |
FLG ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL008712MO | Mouse Filaggrin(FLG) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.78 pg/mL |
