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FOLH1

FOLH1,即葉酸水解酶1,別名 Cell growth inhibiting protein 27 、Folate hydrolase 1、Folate hydrolase,是一種關鍵的葉酸代謝酶。它由FOLH1基因編碼,分布在前列腺、腦、肺、肝等多種組織中。FOLH1通過水解葉酸多聚谷氨酸鹽,調節細胞內葉酸水平,對DNA合成和修復至關重要。其異常表達與前列腺癌等腫瘤的發生發展關聯,使其成為潛在的治療靶點。此外,FOLH1在神經退行性疾病中也有研究價值,其活性變化可能與多巴胺神經元損失有關,對細胞代謝和增殖具有重要調控作用。

熱銷產品

Recombinant Human Glutamate carboxypeptidase 2 (FOLH1), partial (Active) (CSB-MP008782HU1)

驗證數據

CSB-MP008782HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP008782HU1

Activity
Measured by its binding ability in a functional ELISA.Immobilized Human FOLH1 at 2 μg/ml can bind Anti-FOLH1 recombinant antibody(CSB-RA008782MA1HU). The EC50 is 11.74-15.02 ng/mL.

CSB-MP008782HU1

Activity
Measured by its binding ability in a functional ELISA.Immobilized Human FOLH1 at 2 μg/mL can bind Anti-FOLH1 recombinant antibody(CSB-RA008782MA2HU). The EC50 is 3.853-4.303 ng/mL.

FOLH1 Recombinant Monoclonal Antibody (CSB-RA162924A0HU)

驗證數據

CSB-RA162924A0HU

IHC image of CSB-RA162924A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human Glutamate carboxypeptidase 2(FOLH1) ELISA kit (CSB-EL008782HU)

驗證數據

CSB-EL008782HU 標準曲線

貨號:CSB-EL008782HU

規格:96T/48T

靈敏度:1.2 ng/mL

檢測范圍:4.7 ng/mL-300 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FOLH1 Antibodies

FOLH1 for Homo sapiens (Human)

FOLH1 Proteins

FOLH1 Proteins for Rattus norvegicus (Rat)

FOLH1 Proteins for Homo sapiens (Human)

FOLH1 Proteins for Mus musculus (Mouse)

FOLH1 Proteins for Sus scrofa (Pig)

FOLH1 ELISA Kit

FOLH1 ELISA Kit for Homo sapiens (Human)



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