FRMD5
FRMD5，全稱為含F(xiàn)ERM結(jié)構(gòu)域蛋白5，研究中常直接稱其為FRMD5，部分文獻(xiàn)也會(huì)用F5作為簡(jiǎn)稱。這種蛋白能幫助維持細(xì)胞的正常形態(tài)，讓細(xì)胞之間的連接更穩(wěn)定，還參與細(xì)胞的移動(dòng)過程，輔助細(xì)胞在組織中有序遷移。在疾病方面，F(xiàn)RMD5表達(dá)變化和一些腫瘤進(jìn)展相關(guān)——比如某些癌癥組織里它的含量與正常組織差異明顯，可能影響腫瘤細(xì)胞的擴(kuò)散能力；同時(shí)，它也和神經(jīng)細(xì)胞的生長(zhǎng)、連接形成有關(guān)，或許在神經(jīng)發(fā)育類疾病中起作用。目前針對(duì)它的藥物研發(fā)還處于早期階段，科學(xué)家們正探索通過調(diào)節(jié)其活性來(lái)干預(yù)細(xì)胞異常狀態(tài)，但尚未有進(jìn)入臨床試驗(yàn)的具體藥物。
熱銷產(chǎn)品
FRMD5 Antibody (CSB-PA773602LA01HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: FRMD5 antibody at 16 μg/ml
Lane 1: Mouse kidney tissue
Lane 2: Mouse heart tissue
Lane 3: Mouse skeletal muscle tissue
Lane 4: Mouse lung tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 66, 64 kDa
Observed band size: 65 kDa
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA773602LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA773602LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA773602LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
FRMD5 Antibodies
FRMD5 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA773602LA01HU | FRMD5 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA773602LB01HU | FRMD5 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA773602LC01HU | FRMD5 Antibody, FITC conjugated | Human | |
| CSB-PA773602LD01HU | FRMD5 Antibody, Biotin conjugated | Human | ELISA |
FRMD5 Proteins
FRMD5 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP773602HU1 CSB-EP773602HU1 CSB-BP773602HU1 CSB-MP773602HU1 CSB-EP773602HU1-B |
Recombinant Human FERM domain-containing protein 5 (FRMD5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF773602HU | Recombinant Human FERM domain-containing protein 5 (FRMD5) | in vitro E.coli expression system |
