GAS6
GAS6,全稱為生長停滯特異性蛋白6,常用別名GAS6蛋白。它是一種分泌型糖蛋白,廣泛表達于人體各類組織,參與細胞存活、增殖、分化及凝血調控,同時結合酪氨酸激酶受體,啟動信號傳導,對血管穩態、免疫平衡及組織修復具有重要作用。 GAS6異常表達與多種疾病密切相關,異常高表達會促進腫瘤細胞增殖、侵襲轉移,與肺癌、肝癌、白血病等腫瘤相關;同時與血栓形成、心血管疾病相關。目前GAS6抑制劑處于臨床前研究階段,通過阻斷其信號傳導,為腫瘤及心血管疾病提供治療思路。
熱銷產品
Recombinant Human Growth arrest-specific protein 6 (GAS6) (Active) (CSB-MP619872HUd7)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 at 4 μg/ml can bind Human AXL (CSB-MP326981HUd9). The EC50 is 1.100-1.324 ng/mL.
Activity
Human AXL (CSB-MP326981HUd9) captured on Protein A Chip can bind Recombinant Human GAS6 with an affinity constant of 3.65 nM as detected by MetaSPR Assay (WeSPRTM 200).
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 at 2 μg/ml can bind Anti-GAS6 recombinant antibody (CSB-RA619872MA1HU). The EC50 is 12.31-14.86 ng/mL.
Activity
GAS6 Recombinant Monoclonal Antibody (CSB-RA619872MA1HU) captured on Protein A Chip can bind Recombinant Human GAS6 with an affinity constant of 0.767 nM as detected by MetaSPR Assay (WeSPRTM 200).
Recombinant Macaca fascicularis Growth arrest specific 6 (GAS6) (Active) (CSB-MP5039MOV)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GAS6 at 4 μg/ml can bind Human AXL (CSB-MP326981HUd9). The EC50 is 2.952-3.438 ng/mL.
Activity
Human AXL (CSB-MP326981HUd9) captured on Protein A Chip can bind Recombinant Macaca fascicularis GAS6 with an affinity constant of 1.93 nM as detected by MetaSPR Assay (WeSPRTM 200).
The purity of GAS6 was greater than 95% as determined by SEC-HPLC
GAS6 Recombinant Monoclonal Antibody (CSB-RA619872MA1HU)
驗證數據
The Binding Activity of Human GAS6 with Anti-GAS6 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 (CSB-MP619872HUd7) at 2 μg/mL can bind Anti-GAS6 recombinant antibody. The EC50 is 12.31-14.86 ng/mL.
The Binding Activity of Human GAS6 with Anti-GAS6 Recombinant Antibody
Activity:GAS6 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human GAS6 (CSB-MP619872HUd7) with an affinity constant of 0.767 nM as detected by MetaSPR Assay (WeSPRTM 200).
Human Growth arrest-specific protein 6(GAS6) ELISA kit (CSB-EL009270HU)
驗證數據
貨號:CSB-EL009270HU
規格:96T/48T
靈敏度:0.195 ng/mL
檢測范圍:0.78 ng/mL-50 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
GAS6 Antibodies
GAS6 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002641 | GAS6 Antibody | Human | WB, IHC, ELISA |
| CSB-PA778945 | GAS6 Antibody | Human | ELISA,IHC |
| CSB-PA108949 | GAS6 Antibody | Human | ELISA,IHC |
| CSB-PA619872LA01HU | GAS6 Antibody | Human | ELISA, WB |
| CSB-PA619872LC01HU | GAS6 Antibody, FITC conjugated | Human | |
| CSB-PA619872LD01HU | GAS6 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA619872MA1HU | GAS6 Recombinant Monoclonal Antibody | Human | ELISA, SPR |
GAS6 Proteins
GAS6 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP619872HU CSB-EP619872HU CSB-BP619872HU CSB-MP619872HU CSB-EP619872HU-B |
Recombinant Human Growth arrest-specific protein 6 (GAS6) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP619872HUd7 | Recombinant Human Growth arrest-specific protein 6 (GAS6) (Active) | Mammalian cell |
GAS6 ELISA Kit
GAS6 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL009270HU | Human Growth arrest-specific protein 6(GAS6) ELISA kit | serum, plasma, tissue homogenates | 0.195 ng/mL |




