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GAS6

GAS6,全稱為生長停滯特異性蛋白6,常用別名GAS6蛋白。它是一種分泌型糖蛋白,廣泛表達于人體各類組織,參與細胞存活、增殖、分化及凝血調控,同時結合酪氨酸激酶受體,啟動信號傳導,對血管穩態、免疫平衡及組織修復具有重要作用。 GAS6異常表達與多種疾病密切相關,異常高表達會促進腫瘤細胞增殖、侵襲轉移,與肺癌、肝癌、白血病等腫瘤相關;同時與血栓形成、心血管疾病相關。目前GAS6抑制劑處于臨床前研究階段,通過阻斷其信號傳導,為腫瘤及心血管疾病提供治療思路。

熱銷產品

Recombinant Human Growth arrest-specific protein 6 (GAS6) (Active) (CSB-MP619872HUd7)

驗證數據

CSB-MP619872HUd7

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP619872HUd7

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 at 4 μg/ml can bind Human AXL (CSB-MP326981HUd9). The EC50 is 1.100-1.324 ng/mL.

CSB-MP619872HUd7

Activity
Human AXL (CSB-MP326981HUd9) captured on Protein A Chip can bind Recombinant Human GAS6 with an affinity constant of 3.65 nM as detected by MetaSPR Assay (WeSPRTM 200).

CSB-MP619872HUd7

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 at 2 μg/ml can bind Anti-GAS6 recombinant antibody (CSB-RA619872MA1HU). The EC50 is 12.31-14.86 ng/mL.

CSB-MP619872HUd7

Activity
GAS6 Recombinant Monoclonal Antibody (CSB-RA619872MA1HU) captured on Protein A Chip can bind Recombinant Human GAS6 with an affinity constant of 0.767 nM as detected by MetaSPR Assay (WeSPRTM 200).

Recombinant Macaca fascicularis Growth arrest specific 6 (GAS6) (Active) (CSB-MP5039MOV)

驗證數據

CSB-MP5039MOV

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP5039MOV

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GAS6 at 4 μg/ml can bind Human AXL (CSB-MP326981HUd9). The EC50 is 2.952-3.438 ng/mL.

CSB-MP5039MOV

Activity
Human AXL (CSB-MP326981HUd9) captured on Protein A Chip can bind Recombinant Macaca fascicularis GAS6 with an affinity constant of 1.93 nM as detected by MetaSPR Assay (WeSPRTM 200).

CSB-MP5039MOV

The purity of GAS6 was greater than 95% as determined by SEC-HPLC

GAS6 Recombinant Monoclonal Antibody (CSB-RA619872MA1HU)

驗證數據

CSB-RA619872MA1HU

The Binding Activity of Human GAS6 with Anti-GAS6 Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GAS6 (CSB-MP619872HUd7) at 2 μg/mL can bind Anti-GAS6 recombinant antibody. The EC50 is 12.31-14.86 ng/mL.

CSB-RA619872MA1HU

The Binding Activity of Human GAS6 with Anti-GAS6 Recombinant Antibody
Activity:GAS6 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Recombinant Human GAS6 (CSB-MP619872HUd7) with an affinity constant of 0.767 nM as detected by MetaSPR Assay (WeSPRTM 200).

Human Growth arrest-specific protein 6(GAS6) ELISA kit (CSB-EL009270HU)

驗證數據

CSB-EL009270HU 標準曲線

貨號:CSB-EL009270HU

規格:96T/48T

靈敏度:0.195 ng/mL

檢測范圍:0.78 ng/mL-50 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

GAS6 Antibodies

GAS6 for Homo sapiens (Human)

GAS6 Proteins

GAS6 Proteins for Homo sapiens (Human)

GAS6 ELISA Kit

GAS6 ELISA Kit for Homo sapiens (Human)



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