GC
GC,全稱為組特異性組分蛋白,常用別名是維生素D結合蛋白(DBP)。它主要由肝臟合成并釋放入血,負責結合并轉運體內的維生素D及其代謝產物,同時參與免疫細胞活化與鐵離子代謝,對維持機體鈣磷平衡和正常免疫應答十分關鍵。
GC蛋白水平異常或功能缺陷,會直接影響維生素D的利用效率,易引發佝僂病、骨質疏松等代謝性骨病,也與自身免疫病、慢性炎癥及部分腫瘤易感性相關。目前圍繞GC的研發主要集中在重組蛋白制劑與功能調節劑,部分候選分子已進入臨床前研究階段,旨在改善維生素D利用障礙,為相關代謝和免疫疾病提供新的治療選擇。
熱銷產品
Recombinant Human Vitamin D-binding protein (GC), partial (CSB-YP009306HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP009306HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) GC.
Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP009306HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) GC.
GC Recombinant Monoclonal Antibody (CSB-RA089046A0HU)
驗證數據
Overlay Peak curve showing HepG2 cells stained with CSB-RA089046A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
GC Antibodies
GC for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA07569A0Rb | GC Antibody | Human | ELISA, WB, IHC |
| CSB-PA07569B0Rb | GC Antibody, HRP conjugated | Human | ELISA |
| CSB-PA07569C0Rb | GC Antibody, FITC conjugated | Human | |
| CSB-PA07569D0Rb | GC Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA009306GA01HU | GC Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA009306ESR1HU | GC Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA002082 | GC Antibody | Human,Monkey | WB, ELISA |
| CSB-PA964049 | GC Antibody | Human | ELISA,WB,IHC |
| CSB-PA944210 | GC Antibody | Human | ELISA,IHC |
| CSB-RA089046A0HU | GC Recombinant Monoclonal Antibody | Human | ELISA, FC |
GC Proteins
GC Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009306HU | Recombinant Human Vitamin D-binding protein (GC), partial | Yeast |
| CSB-EP009306HU | Recombinant Human Vitamin D-binding protein (GC), partial | E.coli |
| CSB-BP009306HU CSB-MP009306HU CSB-EP009306HU-B |
Recombinant Human Vitamin D-binding protein (GC), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GC ELISA Kit
GC ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E11859h | Human Vitamin D-binding protein,DBP ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/ml |




