GLP2R
GLP2R是胰高血糖素樣肽2受體的全稱，也被稱為GLP-2R。它屬于G蛋白偶聯(lián)受體超家族，與GLP-1、胰高血糖素和GIP的受體具有較高的同源性。GLP2R主要表達(dá)于胃腸道中，其激活能促進(jìn)腸道血流，增強(qiáng)隱窩細(xì)胞增殖、腸干細(xì)胞擴(kuò)增和腸道生長(zhǎng)。GLP-2R在改善腸道屏障功能方面發(fā)揮著重要作用，尤其適用于短腸綜合征的治療。短腸綜合征是一種因小腸被廣泛切除后導(dǎo)致的營(yíng)養(yǎng)吸收不良的疾病。此外，GLP-2R還能與中樞神經(jīng)系統(tǒng)中的受體結(jié)合，抑制食物攝入，并通過(guò)黑色素皮質(zhì)素受體（MCR4）信號(hào)通路減少胃排空。目前，GLP-2類似物Teduglutide已獲批上市，用于治療成人及兒童短腸綜合征。此外，還有多個(gè)GLP-2R藥物管線處于開(kāi)發(fā)階段，未來(lái)其在胃腸道疾病治療領(lǐng)域有望發(fā)揮更大作用。
熱銷產(chǎn)品
Recombinant Human Glucagon-like peptide 2 receptor (GLP2R) (CSB-CF009515HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GLP2R Antibodies
GLP2R for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA025580 | GLP2R Antibody | Human | ELISA,WB,IHC |
| CSB-PA286159 | GLP2R Antibody | Human | ELISA,IHC |
| CSB-PA009515ESR2HU | GLP2R Antibody | Human | ELISA, IHC |
GLP2R Proteins
GLP2R Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009515HU1 CSB-EP009515HU1 CSB-BP009515HU1 CSB-EP009515HU1-B |
Recombinant Human Glucagon-like peptide 2 receptor (GLP2R), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF009515HU | Recombinant Human Glucagon-like peptide 2 receptor (GLP2R) | in vitro E.coli expression system |
| CSB-MP009515HU1 | Recombinant Human Glucagon-like peptide 2 receptor (GLP2R), partial | Mammalian cell |
| CSB-MP009515HU | Recombinant Human Glucagon-like peptide 2 receptor (GLP2R)-VLPs | Mammalian cell |
| CSB-MP009515HU1-B | Recombinant Human Glucagon-like peptide 2 receptor (GLP2R), partial, Biotinylated | Mammalian cell |
GLP2R Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009515MO1 CSB-EP009515MO1 CSB-BP009515MO1 CSB-MP009515MO1 CSB-EP009515MO1-B |
Recombinant Mouse Glucagon-like peptide 2 receptor (Glp2r), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009515MO | Recombinant Mouse Glucagon-like peptide 2 receptor (Glp2r) | in vitro E.coli expression system |
GLP2R Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009515RA1 CSB-EP009515RA1 CSB-BP009515RA1 CSB-MP009515RA1 CSB-EP009515RA1-B |
Recombinant Rat Glucagon-like peptide 2 receptor (Glp2r), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009515RA | Recombinant Rat Glucagon-like peptide 2 receptor (Glp2r) | in vitro E.coli expression system |
