GNAQ
GNAQ,全稱為G蛋白α亞基Q,常用別名GαQ。它是細胞內G蛋白偶聯受體信號通路的關鍵組成部分,廣泛表達于人體各類組織,參與信號傳導、細胞增殖、分化及代謝調控,能夠介導多種細胞外信號向細胞內傳遞,維持機體正常生理功能。 GNAQ突變及功能異常與多種疾病密切相關,突變會導致信號通路過度激活,促進細胞異常增殖,與葡萄膜黑色素瘤、皮膚黑色素瘤等腫瘤相關;同時與遺傳性疾病、心血管疾病相關。目前GNAQ抑制劑處于臨床前及早期臨床研究階段,通過阻斷異常信號傳導,為腫瘤及遺傳性疾病提供治療方案。
熱銷產品
Recombinant Human Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) (CSB-BP342271HUn8)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GNAQ Recombinant Monoclonal Antibody (CSB-RA106255A0HU)
驗證數據
Flow cytometric analysis of G protein subunit alpha q expression in C2C12 cells using G protein subunit alpha q antibody. Green, isotype control; red, G protein subunit alpha q.
Immunocytochemical staining of C2C12 cells with G protein subunit alpha q antibody. Nuclei were stained blue with DAPI; G protein subunit alpha q was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
Western blotting analysis using G protein subunit alpha q antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with G protein subunit alpha q antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
GNAQ Antibody (CSB-PA009594LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA009594LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA009594LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
GNAQ Antibodies
GNAQ for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA009594GA01HU | GNAQ Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA009594LA01HU | GNAQ Antibody | Human | ELISA, IHC, IF |
| CSB-PA009594LB01HU | GNAQ Antibody, HRP conjugated | Human | ELISA |
| CSB-PA009594LC01HU | GNAQ Antibody, FITC conjugated | Human | |
| CSB-RA106255A0HU | GNAQ Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, FC, ICC |
GNAQ Proteins
GNAQ Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009594RA CSB-EP009594RA CSB-BP009594RA CSB-MP009594RA CSB-EP009594RA-B |
Recombinant Rat Guanine nucleotide-binding protein G (q) subunit alpha (Gnaq) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GNAQ Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009594MO CSB-BP009594MO CSB-MP009594MO CSB-EP009594MO-B |
Recombinant Mouse Guanine nucleotide-binding protein G (q) subunit alpha (Gnaq) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009594MO | Recombinant Mouse Guanine nucleotide-binding protein G (q) subunit alpha (Gnaq) | E.coli |
GNAQ Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP330878XBE CSB-EP330878XBE CSB-BP330878XBE CSB-MP330878XBE CSB-EP330878XBE-B |
Recombinant Xenopus laevis Guanine nucleotide-binding protein G (q) subunit alpha | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GNAQ Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP342271HU CSB-MP342271HU CSB-EP342271HU-B |
Recombinant Human Guanine nucleotide-binding protein G (q) subunit alpha (GNAQ) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP342271HU | Recombinant Human Guanine nucleotide-binding protein G (q) subunit alpha (GNAQ) | E.coli |
| CSB-BP342271HUn8 | Recombinant Human Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) | Baculovirus |
| CSB-BP342271HU | Recombinant Human Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) | Baculovirus |
| CSB-EP342271HUc7 | Recombinant Human Guanine nucleotide-binding protein G (q) subunit alpha (GNAQ) | E.coli |
| CSB-YP342271HU1c7 | Recombinant Human Guanine nucleotide-binding protein G (q) subunit alpha (GNAQ), partial | Yeast |
| CSB-YP342271HU1 | Recombinant Human Guanine nucleotide-binding protein G (q) subunit alpha (GNAQ), partial | Yeast |
GNAQ Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP636716DO CSB-EP636716DO CSB-BP636716DO CSB-MP636716DO CSB-EP636716DO-B |
Recombinant Dog Guanine nucleotide-binding protein G (q) subunit alpha (GNAQ) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GNAQ Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP647681PI CSB-EP647681PI CSB-BP647681PI CSB-MP647681PI CSB-EP647681PI-B |
Recombinant Pig Guanine nucleotide-binding protein G (q) subunit alpha (GNAQ) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |




