GPR18
GPR18，全稱為 G 蛋白偶聯受體 18，常用別名大麻素相關受體。它廣泛表達于免疫細胞、神經系統、血管平滑肌等組織，參與機體免疫功能調節、炎癥反應抑制、血管張力調控以及神經信號傳導，能夠穩定神經、血管、免疫系統整體生理平衡，維持機體穩態。
GPR18 功能異常紊亂與慢性炎癥、神經病理性疼痛、多發性硬化、動脈粥樣硬化以及淋巴瘤等疾病密切相關，受體異?；罨瘯觿∶庖呶蓙y與慢性炎癥損傷，加重神經疼痛癥狀。目前 GPR18 選擇性激動劑、阻斷拮抗劑均處于臨床前研發階段，通過精準調控受體活性，有望用于慢性炎癥、神經疼痛疾病以及血液惡性腫瘤的治療開發。
熱銷產品
GPR18 Antibody (CSB-PA614525LA01HU)
驗證數據
Western blot
All lanes: GPR18 antibody at 8µg/ml + Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 39 kDa
Observed band size: 39 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA614525LA01HU at dilution of 1:100
Immunofluorescent analysis of U251 cells using CSB-PA614525LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
GPR18 Antibodies
GPR18 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002772 | GPR18 Antibody | Human | WB, IF, ELISA |
| CSB-PA008914 | GPR18 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA614525LA01HU | GPR18 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA614525LD01HU | GPR18 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA614525LC01HU | GPR18 Antibody, FITC conjugated | Human | |
| CSB-PA614525LB01HU | GPR18 Antibody, HRP conjugated | Human | ELISA |
GPR18 Proteins
GPR18 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009789RA1 CSB-EP009789RA1 CSB-BP009789RA1 CSB-MP009789RA1 CSB-EP009789RA1-B |
Recombinant Rat N-arachidonyl glycine receptor (Gpr18), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009789RA | Recombinant Rat N-arachidonyl glycine receptor (Gpr18) | in vitro E.coli expression system |
GPR18 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP614525HU1 CSB-EP614525HU1 CSB-BP614525HU1 CSB-MP614525HU1 CSB-EP614525HU1-B |
Recombinant Human N-arachidonyl glycine receptor (GPR18), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF614525HU | Recombinant Human N-arachidonyl glycine receptor (GPR18) | in vitro E.coli expression system |
GPR18 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP660985BO1 CSB-EP660985BO1 CSB-BP660985BO1 CSB-MP660985BO1 CSB-EP660985BO1-B |
Recombinant Bovine N-arachidonyl glycine receptor (GPR18), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF660985BO | Recombinant Bovine N-arachidonyl glycine receptor (GPR18) | in vitro E.coli expression system |
GPR18 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP689968MOV1 CSB-EP689968MOV1 CSB-BP689968MOV1 CSB-MP689968MOV1 CSB-EP689968MOV1-B |
Recombinant Macaca fascicularis N-arachidonyl glycine receptor (GPR18), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF689968MOV | Recombinant Macaca fascicularis N-arachidonyl glycine receptor (GPR18) | in vitro E.coli expression system |
GPR18 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP810372MO1 CSB-EP810372MO1 CSB-BP810372MO1 CSB-MP810372MO1 CSB-EP810372MO1-B |
Recombinant Mouse N-arachidonyl glycine receptor (Gpr18), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF810372MO | Recombinant Mouse N-arachidonyl glycine receptor (Gpr18) | in vitro E.coli expression system |
