GPR4
GPR4，全稱為G蛋白偶聯(lián)受體4，是一種廣泛存在于人體細(xì)胞表面的受體蛋白。該蛋白具有多種別名，包括GPCR GPR4、G protein coupled receptor 19、G protein coupled receptor 4等。GPR4蛋白主要參與細(xì)胞外pH值變化的感知，并觸發(fā)細(xì)胞內(nèi)信號(hào)傳導(dǎo)，從而影響多種生理過程。例如，GPR4蛋白在炎癥性疾病的發(fā)病和進(jìn)展、神經(jīng)性疼痛、腫瘤細(xì)胞代謝和侵襲等方面發(fā)揮重要作用。近年來，GPR4蛋白成為新的治療靶點(diǎn)，相關(guān)藥物研發(fā)取得顯著進(jìn)展。例如，針對(duì)GPR4蛋白的激動(dòng)劑和拮抗劑被用于治療炎癥性疾病、神經(jīng)性疼痛和腫瘤等疾病。此外，GPR4蛋白在心血管疾病、肥胖和衰老等疾病中也具有潛在的治療價(jià)值。相關(guān)藥物的研發(fā)為這些疾病的治療提供了新的思路和方法。
熱銷產(chǎn)品
GPR4 Antibody (CSB-PA009813LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA009813LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA009813LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
GPR4 Antibodies
GPR4 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009813LA01HU | GPR4 Antibody | Human | ELISA, IHC, IF |
| CSB-PA009813LB01HU | GPR4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA009813LC01HU | GPR4 Antibody, FITC conjugated | Human | |
| CSB-PA009813LD01HU | GPR4 Antibody, Biotin conjugated | Human | ELISA |
GPR4 Proteins
GPR4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009813HU1 CSB-EP009813HU1 CSB-BP009813HU1 CSB-MP009813HU1 CSB-EP009813HU1-B |
Recombinant Human G-protein coupled receptor 4 (GPR4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009813HU | Recombinant Human G-protein coupled receptor 4 (GPR4) | in vitro E.coli expression system |
GPR4 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009813PI1 CSB-EP009813PI1 CSB-BP009813PI1 CSB-MP009813PI1 CSB-EP009813PI1-B |
Recombinant Pig G-protein coupled receptor 4 (GPR4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009813PI | Recombinant Pig G-protein coupled receptor 4 (GPR4) | in vitro E.coli expression system |
GPR4 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP629692BO1 CSB-EP629692BO1 CSB-BP629692BO1 CSB-MP629692BO1 CSB-EP629692BO1-B |
Recombinant Bovine G-protein coupled receptor 4 (GPR4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF629692BO | Recombinant Bovine G-protein coupled receptor 4 (GPR4) | in vitro E.coli expression system |
GPR4 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP807408MO1 CSB-EP807408MO1 CSB-BP807408MO1 CSB-MP807408MO1 CSB-EP807408MO1-B |
Recombinant Mouse G-protein coupled receptor 4 (Gpr4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF807408MO | Recombinant Mouse G-protein coupled receptor 4 (Gpr4) | in vitro E.coli expression system |
