HLA-DRA
HLA-DRA，全稱為人類白細(xì)胞抗原DRα鏈，常見別名包括HLA-DR1A等。它是人體免疫系統(tǒng)里的關(guān)鍵分子，常與β鏈結(jié)合形成復(fù)合物分布在細(xì)胞表面，核心作用是把細(xì)胞內(nèi)或外界入侵的抗原片段展示出來(lái)，供T細(xì)胞識(shí)別，幫助免疫系統(tǒng)區(qū)分自身組織和外來(lái)異物，維持免疫平衡。
HLA-DRA結(jié)構(gòu)或表達(dá)異常可能引發(fā)免疫識(shí)別紊亂，與多種疾病相關(guān)：比如類風(fēng)濕關(guān)節(jié)炎、系統(tǒng)性紅斑狼瘡等自身免疫病患者中，常能檢測(cè)到它的特定變異類型；器官移植時(shí)，它的匹配程度直接影響移植后的排斥風(fēng)險(xiǎn)。目前針對(duì)它的藥物研發(fā)多圍繞調(diào)節(jié)免疫反應(yīng)展開，例如開發(fā)抑制過(guò)度免疫激活的制劑，用于緩解自身免疫病癥狀或降低移植排斥概率，不過(guò)這些藥物大多仍處于臨床試驗(yàn)階段，尚未廣泛應(yīng)用于臨床。
熱銷產(chǎn)品
Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) (CSB-EP360793HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HLA-DRA Recombinant Monoclonal Antibody (CSB-RA188867A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Raji whole cell lysate(30μg)
All lanes: HLA DRA antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/40000 dilution
Predicted band size: 29 kDa
Observed band size: 35 kDa
Exposure time：2min40s
Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) ELISA kit (CSB-EL010497HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL010497HU
規(guī)格：96T/48T
靈敏度：4.68 pg/mL
檢測(cè)范圍：18.75 pg/mL-1200 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
HLA-DRA Antibodies
HLA-DRA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA17939C0Rb | HLA-DRA Antibody, FITC conjugated | Human | |
| CSB-PA17939A0Rb | HLA-DRA Antibody | Human | ELISA, IHC |
| CSB-PA17939B0Rb | HLA-DRA Antibody, HRP conjugated | Human | ELISA |
| CSB-RA188867A0HU | HLA-DRA Recombinant Monoclonal Antibody | Human | ELISA, WB |
HLA-DRA Proteins
HLA-DRA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP360793HU | Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) | Yeast |
| CSB-EP360793HU1 | Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA), partial | E.coli |
| CSB-EP360793HU | Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) | E.coli |
| CSB-BP360793HU CSB-MP360793HU CSB-EP360793HU-B |
Recombinant Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HLA-DRA ELISA Kit
HLA-DRA ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL010497HU | Human HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) ELISA kit | serum, plasma, tissue homogenates | 4.68 pg/mL |
