IGSF11
IGSF11，全稱(chēng)免疫球蛋白超家族成員11（Immunoglobulin superfamily member 11），常見(jiàn)別名為VSIG3、BT-IgSF等。該蛋白主要表達(dá)于睪丸和大腦的質(zhì)膜上，參與突觸傳遞和可塑性的調(diào)控。IGSF11在神經(jīng)元中發(fā)揮作用，與突觸形成和功能密切相關(guān)，其缺失會(huì)導(dǎo)致突觸傳遞中斷。研究表明，IGSF11可能通過(guò)與其他蛋白相互作用，影響神經(jīng)遞質(zhì)的釋放和受體功能。此外，IGSF11與多種神經(jīng)系統(tǒng)疾病相關(guān)，如阿爾茨海默病和帕金森病，其在疾病發(fā)生發(fā)展中的作用正受到廣泛關(guān)注。目前，針對(duì)IGSF11的藥物研發(fā)尚處于早期階段，部分研究嘗試通過(guò)基因編輯或小分子抑制劑干預(yù)其功能，以期治療相關(guān)神經(jīng)系統(tǒng)疾病。未來(lái)，隨著對(duì)IGSF11作用機(jī)制的深入理解，有望開(kāi)發(fā)出更有效的治療策略。
熱銷(xiāo)產(chǎn)品
Recombinant Human Immunoglobulin superfamily member 11 (IGF1R), partial (CSB-MP691547HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
IGSF11 Antibodies
IGSF11 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA011557GA01HU | IGSF11 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA691547LA01HU | IGSF11 Antibody | Human, Mouse | ELISA, WB |
| CSB-PA691547LD01HU | IGSF11 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA691547LC01HU | IGSF11 Antibody, FITC conjugated | Human | |
| CSB-PA691547LB01HU | IGSF11 Antibody, HRP conjugated | Human | ELISA |
IGSF11 Proteins
IGSF11 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP691547HU CSB-EP691547HU CSB-BP691547HU CSB-EP691547HU-B |
Recombinant Human Immunoglobulin superfamily member 11 (IGSF11), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP691547HU | Recombinant Human Immunoglobulin superfamily member 11 (IGF1R), partial | Mammalian cell |
