IL4I1
IL4I1，全稱為白介素4誘導的1型蛋白，常見別名包括L-氨基酸氧化酶4。它是一種具有酶活性的分子，能對特定氨基酸進行氧化代謝，進而影響免疫細胞的狀態。在腫瘤微環境中，這種蛋白常高表達，通過消耗局部的關鍵氨基酸，削弱T細胞的活性，讓腫瘤細胞得以躲避免疫系統的清除。臨床研究發現，IL4I1在乳腺癌、結直腸癌、黑色素瘤等多種癌癥中表達升高，與腫瘤進展和患者不良預后相關。目前，針對IL4I1的治療策略正在探索，一些抑制其活性的小分子藥物和抗體已進入早期臨床試驗階段，期望通過阻斷它的功能來恢復免疫細胞對腫瘤的殺傷能力，為癌癥治療開辟新的方向。
熱銷產品
Recombinant Human L-amino-acid oxidase (IL4I1), partial (CSB-EP850426HU1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
IL4I1 Antibody (CSB-PA850426LA01HU)
驗證數據
Western Blot
Positive WB detected in: HL-60 whole cell lysate(30μg)
All lanes: IL4I1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/40000 dilution
Predicted band size: 62,65 kDa
Observed band size: 70 kDa
Exposure time: 40s
IL4I1 Antibodies
IL4I1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA008635 | IL4I1 Antibody | Human | WB, ELISA |
| CSB-PA850426LA01HU | IL4I1 Antibody | Human | ELISA, WB |
| CSB-PA850426LB01HU | IL4I1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA850426LC01HU | IL4I1 Antibody, FITC conjugated | Human | |
| CSB-PA850426LD01HU | IL4I1 Antibody, Biotin conjugated | Human | ELISA |
IL4I1 Proteins
IL4I1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP850426HU CSB-EP850426HU CSB-BP850426HU CSB-MP850426HU CSB-EP850426HU-B |
Recombinant Human L-amino-acid oxidase (IL4I1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP850426HU1 | Recombinant Human L-amino-acid oxidase (IL4I1), partial | E.coli |
| CSB-EP850426HU1d7 | Recombinant Human L-amino-acid oxidase (IL4I1), partial | E.coli |
| CSB-EP850426HU1g5 | Recombinant Human L-amino-acid oxidase (IL4I1), partial | E.coli |
