KCND2
KCND2，全稱為鉀電壓門控通道亞家族D成員2，常用別名是Kv4.2。這個蛋白主要分布在中樞神經系統的神經細胞中，能調控鉀離子在細胞膜上的流動，進而影響神經細胞的電活動狀態，對大腦的信號傳遞和信息整合起著關鍵作用。
當KCND2功能出現異常時，可能干擾神經細胞的正常工作模式，與部分神經系統疾病相關——比如一些癲癇病例中，該蛋白的表達或活性會發生改變；它也被認為和某些認知功能障礙存在潛在聯系。目前針對這類蛋白的藥物研發仍在探索階段，一些候選化合物試圖通過調節其活性改善相關癥狀，但大多處于實驗室研究或早期臨床測試環節，尚未有成熟藥物應用于臨床。
熱銷產品
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
KCND2 Antibody (CSB-PA873715DSR1HU)
驗證數據
Western blot
All lanes: KCND2 antibody at 0.83µg/ml + THP-1 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 71 kDa
Observed band size: 71 kDa
KCND2 Antibodies
KCND2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA012023GA01HU | KCND2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA010505 | Phospho-KCND2 (S616) Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA010506 | KCND2 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA873715DSR1HU | KCND2 Antibody | Human | ELISA, WB |
| CSB-PA873715DSR2HU | KCND2 Antibody | Human | ELISA, IHC |
KCND2 Proteins
KCND2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP873715HU CSB-EP873715HU CSB-BP873715HU CSB-MP873715HU CSB-EP873715HU-B |
Recombinant Human Potassium voltage-gated channel subfamily D member 2 (KCND2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP012023HU | Recombinant Human Potassium voltage-gated channel subfamily D member 2 (KCND2), partial | Yeast |
| CSB-CF873715HU | Recombinant Human Potassium voltage-gated channel subfamily D member 2 (KCND2) | in vitro E.coli expression system |
| CSB-EP012023HU CSB-BP012023HU CSB-MP012023HU CSB-EP012023HU-B |
Recombinant Human Potassium voltage-gated channel subfamily D member 2 (KCND2), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
